Non-IgE- or Mixed IgE/Non-IgE-Mediated Gastrointestinal Food Allergies in the First Years of Life: Old and New Tools for Diagnosis.

IgG and IgG4 allergen-specific lymphocyte stimulation test atopy patch test clinical score endoscopy eosinophilic gastrointestinal disorders fecal biomarkers non-IgE gastrointestinal food allergy oral food challenge

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
14 Jan 2021
Historique:
received: 25 11 2020
revised: 06 01 2021
accepted: 09 01 2021
entrez: 20 1 2021
pubmed: 21 1 2021
medline: 4 9 2021
Statut: epublish

Résumé

non-IgE and mixed gastrointestinal food allergies present various specific, well-characterized clinical pictures such as food protein-induced allergic proctocolitis, food protein-induced enterocolitis and food protein-induced enteropathy syndrome as well as eosinophilic gastrointestinal disorders such as eosinophilic esophagitis, allergic eosinophilic gastroenteritis and eosinophilic colitis. The aim of this article is to provide an updated review of their different clinical presentations, to suggest a correct approach to their diagnosis and to discuss the usefulness of both old and new diagnostic tools, including fecal biomarkers, atopy patch tests, endoscopy, specific IgG and IgG4 testing, allergen-specific lymphocyte stimulation test (ALST) and clinical score (CoMiss).

Identifiants

pubmed: 33466746
pii: nu13010226
doi: 10.3390/nu13010226
pmc: PMC7829867
pii:
doi:

Substances chimiques

Immunoglobulin E 37341-29-0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Mauro Calvani (M)

Operative Unit of Pediatrics, S. Camillo-Forlanini Hospital, 00152 Rome, Italy.

Caterina Anania (C)

Immunology and Allergology Unit, Department of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.

Barbara Cuomo (B)

Operative Complex Unit of Pediatrics, Belcolle Hospital, 00100 Viterbo, Italy.

Enza D'Auria (E)

Department of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.

Fabio Decimo (F)

Department of Woman, Child and of General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80100 Naples, Italy.

Giovanni Cosimo Indirli (GC)

Pediatrician and Allergoimmunologist, Regional Coordinator of the Italian Society of Pediatric Allergology and Immunology (SIAIP) for Regions Puglia and Basilicata, 73100 Lecce, Italy.

Gianluigi Marseglia (G)

Pediatric Clinic, Pediatrics Department, Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy.

Violetta Mastrorilli (V)

Operative Complex Unit of Pediatrics and Emergency, Giovanni XXIII Hospital, 70056 Bari, Italy.

Marco Ugo Andrea Sartorio (MUA)

Department of Pediatrics, Vittore Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.

Angelica Santoro (A)

Pediatric Clinic, Mother-Child Department, University of Parma, 43121 Parma, Italy.

Elisabetta Veronelli (E)

Food Allergy Committee of the Italian Society of Pediatric Allergy and Immunology (SIAIP), Pediatric Department, Garbagnate Milanese Hospital, ASST Rhodense, 70056 Garbagnate Milanese, Italy.

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