Nursing Procedures for the Prevention and Treatment of Mucositis Induced by Cancer Therapies: Clinical Practice Guideline Based on an Interdisciplinary Consensus Process and a Systematic Literature Search.

chemotherapy complementary integrative medicine mucositis naturopathic radiotherapy side effects stomatitis

Journal

Integrative cancer therapies
ISSN: 1552-695X
Titre abrégé: Integr Cancer Ther
Pays: United States
ID NLM: 101128834

Informations de publication

Date de publication:
Historique:
entrez: 20 1 2021
pubmed: 21 1 2021
medline: 12 10 2021
Statut: ppublish

Résumé

Patients with cancer receiving tumor therapy often suffer from oral mucositis. The aim of this project was to summarize experiences with nursing procedures by experts in integrative oncology and to establish recommendations for nursing interventions that can prevent or cure mucositis. The study design was an interdisciplinary consensus process based on a systematic literature search. The panel discussed and agreed on 19 nursing procedures, which included mouthwashes, such as teas, supplements, oil applications, and different kinds of ice cubes to suck, as well as flaxseed solution, propolis, and mare milk. Twelve interventions were classified as effective, with effectiveness for OraLife, propolis, sea buckthorn pulp oil, marshmallow root tea also for xerostomia, Helago chamomile oil, mare milk, and Saliva Natura rated as highly effective in clinical experience. In the systematic literature search, a total of 12 out of 329 randomized controlled trials and meta-analyses on chamomile (n = 3), The current evidence supports the use of some nursing procedures (f.e. propolis for 2 and 3 grade mucositis) for improving oral mucositis during cancer therapies. There is still a need to define general clinical practice guidelines for the supportive treatment of mucositis, as well as for more interdisciplinary research in this area.

Sections du résumé

BACKGROUND
Patients with cancer receiving tumor therapy often suffer from oral mucositis.
OBJECTIVES
The aim of this project was to summarize experiences with nursing procedures by experts in integrative oncology and to establish recommendations for nursing interventions that can prevent or cure mucositis.
METHODS
The study design was an interdisciplinary consensus process based on a systematic literature search.
RESULTS
The panel discussed and agreed on 19 nursing procedures, which included mouthwashes, such as teas, supplements, oil applications, and different kinds of ice cubes to suck, as well as flaxseed solution, propolis, and mare milk. Twelve interventions were classified as effective, with effectiveness for OraLife, propolis, sea buckthorn pulp oil, marshmallow root tea also for xerostomia, Helago chamomile oil, mare milk, and Saliva Natura rated as highly effective in clinical experience. In the systematic literature search, a total of 12 out of 329 randomized controlled trials and meta-analyses on chamomile (n = 3),
CONCLUSIONS
The current evidence supports the use of some nursing procedures (f.e. propolis for 2 and 3 grade mucositis) for improving oral mucositis during cancer therapies. There is still a need to define general clinical practice guidelines for the supportive treatment of mucositis, as well as for more interdisciplinary research in this area.

Identifiants

pubmed: 33467951
doi: 10.1177/1534735420940412
pmc: PMC7960907
doi:

Substances chimiques

Antineoplastic Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1534735420940412

Commentaires et corrections

Type : CommentIn

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Auteurs

Diana Steinmann (D)

Medizinische Hochschule Hannover, Hannover, Germany.

Burcu Babadağ Savaş (B)

Medizinische Hochschule Hannover, Hannover, Germany.

Sabine Felber (S)

Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

Sosamma Joy (S)

Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

Isabelle Mertens (I)

Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

Holger Cramer (H)

Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

Anna Paul (A)

Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

Monika Layer (M)

Kantonsspital St. Gallen, Centre for Integrative Medicine, Sankt Gallen, Switzerland.

Nadja Klafke (N)

University Hospital Heidelberg, Heidelberg, Germany.

Regina Stolz (R)

University Hospital Tuebingen, Baden-Württemberg, Germany.
Tropenklinik Paul-Lechler-Krankenhaus, Tuebingen, Germany.

Ute Heyder (U)

Community Hospital Karlsruhe, Karlsruhe, Baden-Württemberg, Germany.

Petra Neuberger (P)

University Hospital Heidelberg, Heidelberg, Germany.

Marcela Winkler (M)

Robert-Bosch-Krankenhaus Stuttgart, Stuttgart, Baden-Württemberg, Germany.

Christel Idler (C)

Robert-Bosch-Krankenhaus Stuttgart, Stuttgart, Baden-Württemberg, Germany.

Rolf Heine (R)

Akademie für Pflegeberufe an der Filderklinik, Filderstadt, Germany.

Elke Kaschdailewitsch (E)

Akademie für Pflegeberufe an der Filderklinik, Filderstadt, Germany.

Heike John (H)

Medizinische Hochschule Hannover, Hannover, Germany.

Beeke Schmeling (B)

Medizinische Hochschule Hannover, Hannover, Germany.

Tatjana Zielke (T)

Medizinische Hochschule Hannover, Hannover, Germany.

Markus Horneber (M)

Paracelsus Medical University, Klinikum Nürnberg, Germany.

Claudia M Witt (CM)

University Hospital Zurich and University of Zurich, Zurich, Switzerland.

Petra Voiss (P)

Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

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