[Pathological Complete Response in a Case of Advanced Gastric Cancer with Para-Aortic Lymph Nodes Metastasis Treated by Preoperative Chemotherapy with S-1 and Oxaliplatin(SOX Therapy)].


Journal

Gan to kagaku ryoho. Cancer & chemotherapy
ISSN: 0385-0684
Titre abrégé: Gan To Kagaku Ryoho
Pays: Japan
ID NLM: 7810034

Informations de publication

Date de publication:
Dec 2020
Historique:
entrez: 20 1 2021
pubmed: 21 1 2021
medline: 22 1 2021
Statut: ppublish

Résumé

The patient was a 73-year-old man, diagnosed as advanced gastric cancer with para-aortic lymph nodes(PAN)metastasis. He was treated by 3 courses of neoadjuvant chemotherapy(NAC)with S-1 and oxaliplatin(SOX therapy). CT showed significant reduction of both primary tumor and metastatic lymph nodes. We performed distal gastrectomy with D2 plus PAN dissection. The histopathological findings showed no residual viable tumor cell. The pathological effect of chemotherapy was judged Grade 3(pCR)in both primary tumor and dissected lymph nodes. He is alive without recurrence 21 months after surgery.

Identifiants

pubmed: 33468933

Substances chimiques

Drug Combinations 0
Oxaliplatin 04ZR38536J
Tegafur 1548R74NSZ
Oxonic Acid 5VT6420TIG

Types de publication

Case Reports Journal Article

Langues

jpn

Sous-ensembles de citation

IM

Pagination

2278-2280

Auteurs

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Classifications MeSH