Downregulation of hepatitis C virus replication by miR-196a using lentiviral vectors.
HCV replication
lentiviral vectors
luciferase assay
miR-196a
Journal
Microbiology and immunology
ISSN: 1348-0421
Titre abrégé: Microbiol Immunol
Pays: Australia
ID NLM: 7703966
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
revised:
25
11
2020
received:
23
09
2020
accepted:
08
01
2021
pubmed:
21
1
2021
medline:
22
9
2021
entrez:
20
1
2021
Statut:
ppublish
Résumé
Hepatitis C virus (HCV) is a positive-sense, single-stranded RNA virus that causes chronic hepatitis and hepatocellular carcinoma. Cellular microRNAs (miRNAs) directly modulate the viral infectivity and indirectly through targeting virus-related host factors. They play an essential role in the progression of different stages of HCV infection. The roles of miR-196 family in HCV infection and hepatocellular carcinoma progression remain poorly understood. Using ViTa databases, miR-196a as a high-score miRNA targeting the NS
Identifiants
pubmed: 33470443
doi: 10.1111/1348-0421.12875
doi:
Substances chimiques
MIRN196 microRNA, human
0
MicroRNAs
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
161-170Subventions
Organisme : Professor Alborzi Clinical Microbiology Research Center, Shiraz, Iran
ID : 9515
Organisme : Professor Alborzi Clinical Microbiology Research Center
Informations de copyright
© 2021 The Societies and John Wiley & Sons Australia, Ltd.
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