Worse glycemic control, higher rates of diabetic ketoacidosis, and more hospitalizations in children, adolescents, and young adults with type 1 diabetes and anxiety disorders.


Journal

Pediatric diabetes
ISSN: 1399-5448
Titre abrégé: Pediatr Diabetes
Pays: Denmark
ID NLM: 100939345

Informations de publication

Date de publication:
05 2021
Historique:
revised: 27 09 2020
received: 20 07 2020
accepted: 30 11 2020
pubmed: 21 1 2021
medline: 18 1 2022
entrez: 20 1 2021
Statut: ppublish

Résumé

The aim of the study was to explore the metabolic characteristics and outcome parameters in youth with type 1 diabetes and anxiety disorders. HbA1c levels, rates of severe hypoglycemia, diabetic ketoacidosis (DKA), and hospital admission in children, adolescents, and young adults with type 1 diabetes and an anxiety disorder from 431 diabetes-care-centers participating in the nationwide German/Austrian/Swiss/Luxembourgian diabetes survey DPV were analyzed and compared with youth without anxiety disorders. Children, adolescents, and young adults with type 1 diabetes and anxiety disorders (n = 1325) had significantly higher HbA1c (8.5% vs. 8.2%), higher rates of DKA (4.2 vs. 2.5 per 100 patient-years), and higher hospital admission rates (63.6 vs. 40.0 per 100 patient-years) than youth without anxiety disorders (all p < 0.001). Rates of severe hypoglycemia did not differ. Individuals with anxiety disorders other than needle phobia (n = 771) had higher rates of DKA compared to those without anxiety disorders (4.2 vs. 2.5 per 100 patient-years, p = 0.003) whereas the rate of DKA in individuals with needle phobia (n = 555) was not significantly different compared to those without anxiety disorders. Children, adolescents, and young adults with anxiety disorders other than needle phobia had higher hospitalization rates (73.7 vs. 51.4 per 100 patient-years) and more inpatient days (13.2 vs. 10.1 days) compared to those with needle phobia (all p < 0.001). Children, adolescents, and young adults with type 1 diabetes and anxiety disorders had worse glycemic control, higher rates of DKA, and more hospitalizations compared to those without anxiety disorders. Because of the considerable consequences, clinicians should screen for comorbid anxiety disorders in youth with type 1 diabetes.

Identifiants

pubmed: 33470512
doi: 10.1111/pedi.13177
doi:

Substances chimiques

Glycated Hemoglobin A 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

519-528

Informations de copyright

© 2021 The Authors. Pediatric Diabetes published by John Wiley & Sons Ltd.

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Auteurs

Angela Galler (A)

Sozialpädiatrisches Zentrum, Paediatric Endocrinology and Diabetology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Sascha R Tittel (SR)

Institute for Epidemiology und Medical Biometry, ZIBMT, Universität Ulm, Ulm, Germany.
German Centre for Diabetes Research (DZD), Munich-Neuherberg, Munich, Germany.

Harald Baumeister (H)

Institut für Psychologie und Pädagogik, Klinische Psychologie und Psychotherapie, Universität Ulm, Ulm, Germany.

Christina Reinauer (C)

Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.

Burkhard Brosig (B)

Zentrum für Kinderheilkunde und Jugendmedizin, Familien-und Kinderpsychosomatik, Universitätsklinikum Gießen, Gießen, Germany.

Marianne Becker (M)

Paediatric Clinic, Paediatric Endocrinology and Diabetology (DECCP), Centre Hospitalier de Luxembourg, Luxembourg.

Holger Haberland (H)

Klinik für Kinder- und Jugendmedizin, Paediatric Diabetology, Sana-Kliniken Lichtenberg, Berlin, Germany.

Dörte Hilgard (D)

Kinder- und Jugendarztpraxis Dr. Dörte Hilgard, Witten, Germany.

Marcelus Jivan (M)

CJD Berchtesgaden, Christliches Jugenddorfwerk Deutschland e.V, Germany.

Joaquina Mirza (J)

Kinderkrankenhaus Amsterdamer Straße, Klinik für Kinder- und Jugendmedizin, Paediatric Diabetology, Kliniken Köln, Köln, Germany.

Julia Schwab (J)

Diabetes-Klinik Bad Mergentheim GmbH & Co. KG, Bad Mergentheim, Germany.

Reinhard W Holl (RW)

Institute for Epidemiology und Medical Biometry, ZIBMT, Universität Ulm, Ulm, Germany.
German Centre for Diabetes Research (DZD), Munich-Neuherberg, Munich, Germany.

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