Analysis of the persistence time of the SARS-CoV-2 virus in the cadaver and the risk of passing infection to autopsy staff.


Journal

The Medico-legal journal
ISSN: 2042-1834
Titre abrégé: Med Leg J
Pays: England
ID NLM: 0412004

Informations de publication

Date de publication:
Mar 2021
Historique:
pubmed: 22 1 2021
medline: 17 3 2021
entrez: 21 1 2021
Statut: ppublish

Résumé

The activity of the SARS-CoV-2 virus has not yet been studied in a post-mortem setting. The absence of these data has led to the prohibition of exposure of infected corpses during burial procedures. Our aim was to assess the virus's persistence and the possibility of transmission in the post-mortem phase including autopsy staff. The sample group included 29 patients who were admitted to our Covid-19 Centre who died during hospitalisation and the autopsy staff. All the swabs were subjected to a one-step real-time reverse transcription polymerase chain reaction with cycle threshold (Ct) values. Swab collection was performed at 2 h, 4 h, 6 h, 12 h, over 24 since death. The following were the analysis of patients' swabs: 10 cases were positive 2 h after death; 10 cases positive 4 h after death; 9 cases were found positive 6 h after death; 7 cases positive 12 h after death; 9 cases remained positive 24 h after death. The swabs performed on all the forensic pathologist staff on duty who performed the autopsies were negative. The choice to avoid rituals and the display of corpses before and at the burial procedures given appears cautiously valid due to the persistence of the SARS-CoV-2 virus in the post-mortem period. Although the caution in choosing whether or not to perform an autopsy on infected corpses is acceptable, not to perform autopsies is not biologically supported.

Identifiants

pubmed: 33475037
doi: 10.1177/0025817220980601
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

40-53

Auteurs

Isabella Aquila (I)

Institute of Legal Medicine, Department of Surgical and Medical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Pietrantonio Ricci (P)

Institute of Legal Medicine, Department of Surgical and Medical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Carlo Filippo Bonetta (CF)

Institute of Legal Medicine, Department of Surgical and Medical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Matteo Antonio Sacco (MA)

Institute of Legal Medicine, Department of Surgical and Medical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Federico Longhini (F)

Intensive Care Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Carlo Torti (C)

Infectious and Tropical Diseases Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Maria Mazzitelli (M)

Infectious and Tropical Diseases Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Eugenio Garofalo (E)

Intensive Care Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Andrea Bruni (A)

Intensive Care Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Enrico Maria Trecarichi (EM)

Infectious and Tropical Diseases Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Francesca Serapide (F)

Infectious and Tropical Diseases Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Santo Gratteri (S)

Institute of Legal Medicine, Department of Surgical and Medical Sciences, University "Magna Graecia" of Catanzaro, Italy.

Angela Quirino (A)

Clinical Microbiology Unit, Department of Health Sciences, University "Magna Graecia" of Catanzaro, Italy.

Giorgio Settimo Barreca (GS)

Clinical Microbiology Unit, Department of Health Sciences, University "Magna Graecia" of Catanzaro, Italy.

Ludovico Abenavoli (L)

Department of Health Sciences, University "Magna Graecia" of Catanzaro, Italy.

Vincenzo Arena (V)

Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Istituto di Anatomia Patologica, Università Cattolica Del Sacro Cuore, Rome, Italy.

Antonio Oliva (A)

Department of Health Surveillance and Bioethics, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Aida Giancotti (A)

Clinical Microbiology Unit, Department of Health Sciences, University "Magna Graecia" of Catanzaro, Italy.

Ivo Iavicoli (I)

Department of Public Health, University of Naples Federico II, Naples, Italy.

Maria Carla Liberto (MC)

Clinical Microbiology Unit, Department of Health Sciences, University "Magna Graecia" of Catanzaro, Italy.

Giovanni Matera (G)

Clinical Microbiology Unit, Department of Health Sciences, University "Magna Graecia" of Catanzaro, Italy.

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