A Bio-inspired Multifunctionalized Silk Fibroin.

Fibroins Hydrogels Laminin Rheology
biomimetic chemical modification laminin peptide silk fibroin tissue regeneration

Journal

ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670

Informations de publication

Date de publication:
08 02 2021
Historique:
pubmed: 22 1 2021
medline: 15 5 2021
entrez: 21 1 2021
Statut: ppublish

Résumé

A bio-inspired multifunctionalized silk fibroin (BMS) was synthesized in order to mimic the interaction of nidogen with the type IV collagen and laminin of basement membranes. The designed BMS consists of a motif of laminin α-chain-derived, called IK peptide, and type IV collagen covalently bound to the silk fibroin (SF) by using EDC/NHS coupling and a Cu-free click chemistry reaction, respectively. Silk fibroin was chosen as the main component of the BMS because it is versatile and biocompatible, induces an

Identifiants

DOI: 10.1021/acsbiomaterials.0c01567 PMID: 33476122
pubmed: 33476122
doi: 10.1021/acsbiomaterials.0c01567
doi:

Substances chimiques

Hydrogels 0
Laminin 0
Fibroins 9007-76-5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

507-516

Auteurs

Sofia Santi (S)

Department of Industrial Engineering, University of Trento, via Sommarive 9, 38123 Trento, Italy.
BIOTech Research Center, University of Trento, via delle Regole 101, 38123 Trento, Italy.
ORCID: 0000-0002-5338-2730

Ines Mancini (I)

Laboratory of Bioorganic Chemistry, Department of Physics, University of Trento, via Sommarive 14, 38123 Trento, Italy.

Sandra Dirè (S)

Department of Industrial Engineering, University of Trento, via Sommarive 9, 38123 Trento, Italy.
"Klaus Mueller" Magnetic Resonance Laboratory, Department of Industrial Engineering, University of Trento, Via Sommarive 9, 38123 Trento, Italy.
ORCID: 0000-0002-6000-6231

Emanuela Callone (E)

Department of Industrial Engineering, University of Trento, via Sommarive 9, 38123 Trento, Italy.
"Klaus Mueller" Magnetic Resonance Laboratory, Department of Industrial Engineering, University of Trento, Via Sommarive 9, 38123 Trento, Italy.

Giorgio Speranza (G)

Department of Industrial Engineering, University of Trento, via Sommarive 9, 38123 Trento, Italy.
FBK-irst, Via Sommarive 18, Povo, 38123 Trento, Italy.
IFN - CNR, CSMFO Lab. & FBK CMM, via alla Cascata, 56/C Povo, 38123 Trento, Italy.
ORCID: 0000-0003-1478-0995

Nicola Pugno (N)

Laboratory of Bio-Inspired, Bionic, Nano, Meta Materials & Mechanics, Department of Civil, Environmental and Mechanical Engineering, University of Trento, 38123 Trento, Italy.
School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, E1-4NS London, United Kingdom.
ORCID: 0000-0003-2136-2396

Claudio Migliaresi (C)

Department of Industrial Engineering, University of Trento, via Sommarive 9, 38123 Trento, Italy.
BIOTech Research Center, University of Trento, via delle Regole 101, 38123 Trento, Italy.

Antonella Motta (A)

Department of Industrial Engineering, University of Trento, via Sommarive 9, 38123 Trento, Italy.
BIOTech Research Center, University of Trento, via delle Regole 101, 38123 Trento, Italy.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'arthropode › Soie › Fibroïne › A Bio-inspired Multifunctionalized Silk Fibroin.
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › A Bio-inspired Multifunctionalized Silk Fibroin.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Laminine › A Bio-inspired Multifunctionalized Silk Fibroin.
questionsmedicales.fr › Disciplines des sciences naturelles › Physique › Rhéologie › A Bio-inspired Multifunctionalized Silk Fibroin.