Regenerative Medicine for Equine Musculoskeletal Diseases.
autologous conditioned serum
equine
horse
musculoskeletal
orthopaedic
platelet-rich plasma
regenerative medicine
stem cell
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
19 Jan 2021
19 Jan 2021
Historique:
received:
30
11
2020
revised:
08
01
2021
accepted:
15
01
2021
entrez:
22
1
2021
pubmed:
23
1
2021
medline:
23
1
2021
Statut:
epublish
Résumé
Musculoskeletal injuries and chronic degenerative diseases commonly affect both athletic and sedentary horses and can entail the end of their athletic careers. The ensuing repair processes frequently do not yield fully functional regeneration of the injured tissues but biomechanically inferior scar or replacement tissue, causing high reinjury rates, degenerative disease progression and chronic morbidity. Regenerative medicine is an emerging, rapidly evolving branch of translational medicine that aims to replace or regenerate cells, tissues, or organs to restore or establish normal function. It includes tissue engineering but also cell-based and cell-free stimulation of endogenous self-repair mechanisms. Some regenerative medicine therapies have made their way into equine clinical practice mainly to treat tendon injures, tendinopathies, cartilage injuries and degenerative joint disorders with promising results. However, the qualitative and quantitative spatiotemporal requirements for specific bioactive factors to trigger tissue regeneration in the injury response are still unknown, and consequently, therapeutic approaches and treatment results are diverse. To exploit the full potential of this burgeoning field of medicine, further research will be required and is ongoing. This review summarises the current knowledge of commonly used regenerative medicine treatments in equine patients and critically discusses their use.
Identifiants
pubmed: 33477808
pii: ani11010234
doi: 10.3390/ani11010234
pmc: PMC7832834
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Equine Vet J Suppl. 2011 Nov;(40):7-11
pubmed: 22082439
Disabil Rehabil. 2008;30(20-22):1752-8
pubmed: 18608378
Stem Cell Res Ther. 2017 Dec 22;8(1):288
pubmed: 29273086
Biomed Pharmacother. 2019 Jan;109:2318-2326
pubmed: 30551490
J Orthop Res. 2007 Feb;25(2):230-40
pubmed: 17106885
Vet Immunol Immunopathol. 2014 Apr 15;158(3-4):121-7
pubmed: 24556326
PLoS One. 2012;7(2):e32333
pubmed: 22384219
Vet J. 2011 Sep;189(3):248-56
pubmed: 21665498
J Am Vet Med Assoc. 2007 Mar 15;230(6):885-9
pubmed: 17362165
Vet Surg. 2000 Jan-Feb;29(1):8-16
pubmed: 10653490
Equine Vet J. 2015 Mar;47(2):212-7
pubmed: 24735323
Nat Med. 2005 Apr;11(4):367-8
pubmed: 15812508
Aging Cell. 2014 Feb;13(1):2-7
pubmed: 24256351
PLoS One. 2018 Mar 21;13(3):e0194299
pubmed: 29561898
Equine Vet J. 2014 Sep;46(5):554-9
pubmed: 23927380
Osteoarthritis Cartilage. 2016 Sep;24(9):1629-38
pubmed: 27095417
Stem Cell Res Ther. 2017 Jun 5;8(1):129
pubmed: 28583184
Res Vet Sci. 2010 Apr;88(2):326-32
pubmed: 19720387
J Am Vet Med Assoc. 2004 Apr 1;224(7):1123-7
pubmed: 15074858
Cell Tissue Res. 2014 Feb;355(2):327-35
pubmed: 24258028
Vet Clin North Am Equine Pract. 2005 Dec;21(3):651-72, vii
pubmed: 16297726
Science. 2010 Jan 29;327(5965):580-3
pubmed: 20110505
Equine Vet J. 2011 May;43(3):259-64
pubmed: 21492201
Vet Clin North Am Equine Pract. 2006 Aug;22(2):297-322, vii-viii
pubmed: 16882477
Equine Vet J. 2000 Sep;32(5):369-78
pubmed: 11037257
Equine Vet J. 2012 Nov;44(6):721-5
pubmed: 22506811
Stem Cell Res Ther. 2017 Feb 28;8(1):42
pubmed: 28241885
Osteoarthritis Cartilage. 2016 Dec;24(12):2162-2170
pubmed: 27502245
Front Vet Sci. 2016 Apr 13;3:29
pubmed: 27148544
Equine Vet J. 2019 Sep;51(5):681-687
pubmed: 30623489
Vet Med Int. 2010;2010:250978
pubmed: 20445779
Arthritis Rheum. 2002 Mar;46(3):704-13
pubmed: 11920406
Osteoarthritis Cartilage. 2016 Sep;24(9):1613-21
pubmed: 27084348
Transfusion. 2001 Oct;41(10):1217-24
pubmed: 11606819
Stem Cell Res Ther. 2020 May 20;11(1):187
pubmed: 32434555
Bone. 2006 Dec;39(6):1322-30
pubmed: 16926125
Equine Vet J. 2009 May;41(5):465-73
pubmed: 19642407
Am J Sports Med. 2020 Mar;48(3):612-623
pubmed: 32004077
BMC Musculoskelet Disord. 2018 Jul 18;19(1):230
pubmed: 30021608
Vet Rec. 1985 Jan 19;116(3):66-9
pubmed: 3976145
Equine Vet J. 1991 Jan;23(1):32-6
pubmed: 2015806
Vet Surg. 2005 May-Jun;34(3):231-8
pubmed: 16115079
Stem Cell Res Ther. 2015 Apr 12;6:54
pubmed: 25889095
Cartilage. 2012 Jul;3(3):245-54
pubmed: 26069637
Stem Cell Res Ther. 2013 Jul 22;4(4):85
pubmed: 23876512
Equine Vet J. 2013 Jul;45(4):398-400
pubmed: 23738877
Cell Stem Cell. 2011 Jul 8;9(1):11-5
pubmed: 21726829
Equine Vet J. 2007 Sep;39(5):401-6
pubmed: 17910263
J Cell Biol. 2001 Aug 6;154(3):485-90
pubmed: 11489912
Equine Vet J. 2008 May;40(3):260-5
pubmed: 18267879
PLoS One. 2019 Apr 4;14(4):e0214276
pubmed: 30947253
Vet J. 2006 Jan;171(1):51-69
pubmed: 16427582
Vet Clin North Am Equine Pract. 2010 Aug;26(2):391-405
pubmed: 20699183
Nat Med. 2011 Nov 06;17(12):1674-9
pubmed: 22057346
Vet Comp Orthop Traumatol. 2011;24(1):57-61
pubmed: 21103649
Front Physiol. 2012 Sep 06;3:359
pubmed: 22973239
J Bone Joint Surg Am. 2017 Dec 6;99(23):1987-1998
pubmed: 29206788
Tissue Eng Part A. 2017 May;23(9-10):390-402
pubmed: 28095754
Osteoarthritis Cartilage. 2019 Mar;27(3):365-370
pubmed: 30808484
Equine Vet J. 2003 Jan;35(1):99-102
pubmed: 12553472
Am J Vet Res. 2010 Oct;71(10):1237-45
pubmed: 20919913
J Orthop Res. 2009 Dec;27(12):1675-80
pubmed: 19544397
Cytotherapy. 2011 Apr;13(4):419-30
pubmed: 21105841
Curr Rheumatol Rep. 2013 Nov;15(11):375
pubmed: 24072604
J Am Vet Med Assoc. 2007 May 1;230(9):1340-9
pubmed: 17472561
J Cell Physiol. 2008 May;215(2):329-36
pubmed: 17929245
Adv Healthc Mater. 2020 May;9(10):e1901807
pubmed: 32324336
Vet J. 2004 Jan;167(1):45-52
pubmed: 14623150
Stem Cells Dev. 2008 Dec;17(6):1095-107
pubmed: 19006451
Biochem Biophys Res Commun. 2007 Oct 19;362(2):347-53
pubmed: 17719011
Sports Med Arthrosc Rev. 2015 Sep;23(3):156-61
pubmed: 26225576
J Exp Med. 2005 Mar 21;201(6):871-9
pubmed: 15781579
Maturitas. 2014 Jul;78(3):188-98
pubmed: 24855933
Clin Biomech (Bristol, Avon). 2014 Sep;29(8):898-905
pubmed: 25238685
Equine Vet J. 2012 Sep;44(5):554-8
pubmed: 22168479
Nat Med. 2017 Jun;23(6):775-781
pubmed: 28436958
Equine Vet J. 2010 Jan;42(1):5-9
pubmed: 20121906
J Clin Invest. 2007 Nov;117(11):3224-35
pubmed: 17932565
Trends Biotechnol. 2007 Sep;25(9):409-16
pubmed: 17692415
Vet Clin North Am Equine Pract. 2008 Dec;24(3):591-610, viii
pubmed: 19203703
Osteoarthritis Cartilage. 2015 Apr;23(4):648-60
pubmed: 25575968
Front Vet Sci. 2019 Jun 06;6:178
pubmed: 31245393
Vet Surg. 2008 Oct;37(7):648-55
pubmed: 19134087
Equine Vet J. 2019 Nov;51(6):787-794
pubmed: 30815897
J Cell Physiol. 2007 Dec;213(3):626-34
pubmed: 17786965
J Equine Vet Sci. 2020 Mar;86:102820
pubmed: 32067662
Equine Vet J. 1982 Jul;14(3):185-98
pubmed: 7106081
J S Afr Vet Assoc. 1997 Dec;68(4):125-9
pubmed: 9561496
Vet Comp Orthop Traumatol. 2006;19(1):43-7
pubmed: 16594543
J Equine Vet Sci. 2019 Apr;75:30-34
pubmed: 31002089
J Thromb Haemost. 2008 Aug;6(8):1413-21
pubmed: 18503629
Stem Cells. 2007 Nov;25(11):2739-49
pubmed: 17656645
Vet Res Commun. 2014 Mar;38(1):73-80
pubmed: 24442646
J Immunol. 2001 Sep 1;167(5):2887-94
pubmed: 11509636
Ann N Y Acad Sci. 2010 Mar;1192:230-7
pubmed: 20392241
Vet Res Commun. 2008 Sep;32 Suppl 1:S51-5
pubmed: 18683070
J Orthop Res. 2008 Mar;26(3):322-31
pubmed: 17960654
Vet J. 2012 Jul;193(1):58-66
pubmed: 22104504
Nat Rev Rheumatol. 2017 May;13(5):302-311
pubmed: 28381830
J Vet Med Sci. 2017 Mar 23;79(3):618-622
pubmed: 28190827
Vet Immunol Immunopathol. 2020 Mar;221:109975
pubmed: 32087476
Osteoarthritis Cartilage. 2012 May;20(5):430-439
pubmed: 22155431
Vet J. 2011 Nov;190(2):260-267
pubmed: 21195644
Osteoarthritis Cartilage. 2017 Jul;25(7):1161-1171
pubmed: 28153787
J S Afr Vet Assoc. 2019 May 23;90(0):e1-e9
pubmed: 31170778
J Bone Joint Surg Am. 2012 Dec 5;94(23):e1721-7
pubmed: 23224392
Stem Cells Dev. 2012 Jan 20;21(2):273-83
pubmed: 21410356
Front Bioeng Biotechnol. 2015 Jan 12;2:57
pubmed: 25629029
Biomaterials. 2011 Oct;32(30):7411-31
pubmed: 21764438
Sports Med. 2012 Oct 1;42(10):871-90
pubmed: 22963225
Arthritis Res. 2001;3(2):107-13
pubmed: 11178118
BMC Vet Res. 2016 Sep 07;12(1):191
pubmed: 27604193
Equine Vet J. 1995 Jan;27(1):20-5
pubmed: 7774542
Nature. 2016 Dec 7;540(7632):S55
pubmed: 27926701
Tissue Eng Part B Rev. 2015 Feb;21(1):55-66
pubmed: 24950588
J Extracell Vesicles. 2015 Dec 31;4:30087
pubmed: 26725829
Vet Comp Orthop Traumatol. 2011;24(5):363-9
pubmed: 21887455
Cell Commun Signal. 2011 May 14;9:12
pubmed: 21569606
Vet Surg. 2009 Jun;38(4):543-51
pubmed: 19538678
Equine Vet J. 2010 Oct;42(7):636-42
pubmed: 20840579
Equine Vet J. 2009 Apr;41(4):372-8
pubmed: 19562899
PLoS One. 2012;7(11):e48978
pubmed: 23155437
Stem Cells Transl Med. 2013 Nov;2(11):916-27
pubmed: 24068742
Vet J. 2017 Sep;227:1-7
pubmed: 29031324
Bone Res. 2016 Mar 01;4:15040
pubmed: 26962464
Vet Q. 2016 Jun;36(2):56-62
pubmed: 26828234
Equine Vet J. 2007 Mar;39(2):172-80
pubmed: 17378447
J Am Vet Med Assoc. 2008 May 15;232(10):1515-20
pubmed: 18479242
Curr Stem Cell Res Ther. 2014;9(6):497-503
pubmed: 25175766
Arthritis Res Ther. 2016 Apr 04;18:83
pubmed: 27044395
Cell Transplant. 2011;20(6):925-40
pubmed: 21054934
Open Orthop J. 2012;6:348-51
pubmed: 22888381
Vet Surg. 2017 Feb;46(2):242-248
pubmed: 28146292
Biol Open. 2018 May 10;7(5):
pubmed: 29685993
Stem Cells. 2006 Jun;24(6):1613-9
pubmed: 16769763
Methods Mol Biol. 2016;1416:123-46
pubmed: 27236669
PLoS One. 2013 Sep 25;8(9):e75697
pubmed: 24086616
Equine Vet J. 2009 Nov;41(8):741-6
pubmed: 20095220
Inflamm Res. 2003 Oct;52(10):404-7
pubmed: 14520515
BMC Vet Res. 2016 Jul 01;12(1):135
pubmed: 27369779
Acta Vet Scand. 2013 Apr 18;55:34
pubmed: 23597257
Equine Vet J. 2007 Mar;39(2):143-8
pubmed: 17378443
Vet Clin North Am Equine Pract. 2005 Dec;21(3):673-90, vii
pubmed: 16297727
Equine Vet J. 2012 Nov;44(6):752-61
pubmed: 23106629
Vet Surg. 2010 Jul;39(5):588-93
pubmed: 20459481
Osteoarthritis Cartilage. 2008 Jun;16(6):667-79
pubmed: 18042409
Front Bioeng Biotechnol. 2018 Mar 14;6:22
pubmed: 29594113
Prev Vet Med. 2011 Sep 1;101(3-4):204-18
pubmed: 21733586
Vet Surg. 2013 Jun;42(5):499-510
pubmed: 23631631
Equine Vet J. 2020 Jul;52(4):601-612
pubmed: 31821594
Arthritis Rheum. 2012 Oct;64(10):3231-9
pubmed: 22674062
Regen Med Res. 2013 Dec 02;1(1):7
pubmed: 25984326
Vet J. 2017 Jun;224:76-84
pubmed: 28697880
J Orthop Res. 1991 Sep;9(5):641-50
pubmed: 1870029
Nat Rev Rheumatol. 2013 Oct;9(10):584-94
pubmed: 23881068
Materials (Basel). 2017 Jan 03;10(1):
pubmed: 28772388
Equine Vet J. 2014 Sep;46(5):589-95
pubmed: 23855680
Clin Orthop Relat Res. 2004 Nov;(428):272-85
pubmed: 15534553
Vet Immunol Immunopathol. 2016 Mar;171:57-65
pubmed: 26964718
J Knee Surg. 2014 Dec;27(6):435-42
pubmed: 25172967
Front Vet Sci. 2015 Dec 07;2:67
pubmed: 26664993
Equine Vet J. 2004 May;36(4):346-50
pubmed: 15163043
Equine Vet J. 1994 Jul;26(4):327-30
pubmed: 8575402
Scand J Med Sci Sports. 2011 Aug;21(4):554-61
pubmed: 20459479
Osteoarthritis Cartilage. 2012 Dec;20(12):1484-99
pubmed: 22960092
Cytotherapy. 2006;8(4):315-7
pubmed: 16923606
Orthopedics. 2015 Dec;38(12):e1079-90
pubmed: 26652328
Stem Cells Transl Med. 2015 Oct;4(10):1131-43
pubmed: 26339036
Regen Med. 2014;9(6):743-57
pubmed: 25431911
Equine Vet J. 2013 Nov;45(6):737-44
pubmed: 23527626
Biomaterials. 2014 Aug;35(26):7460-9
pubmed: 24927682
Equine Vet J. 2004 Mar;36(2):167-73
pubmed: 15038441
J Vet Intern Med. 2019 May;33(3):1473-1482
pubmed: 30972832
Trends Mol Med. 2009 Sep;15(9):417-29
pubmed: 19740701
Oxid Med Cell Longev. 2018 Feb 11;2018:3075293
pubmed: 29599894
J Orthop Res. 2019 Jun;37(6):1310-1317
pubmed: 30578639
J Vet Sci. 2015;16(1):47-55
pubmed: 25269714
Vet J. 2010 Apr;184(1):27-36
pubmed: 19369100
Biomaterials. 2020 Dec;261:120302
pubmed: 32932172
Vet Clin North Am Equine Pract. 2016 Aug;32(2):229-47
pubmed: 27449390
Equine Vet J. 2010 Mar;42(2):174-80
pubmed: 20156256
Equine Vet J. 2003 Jun;35(4):402-6
pubmed: 12880009
Theranostics. 2018 Jan 1;8(4):906-920
pubmed: 29463990
Vet Res Commun. 2011 Feb;35(2):103-21
pubmed: 21193959
Am J Vet Res. 2017 Jul;78(7):867-875
pubmed: 28650243
Arthritis Res Ther. 2017 Feb 2;19(1):18
pubmed: 28148295
Am J Sports Med. 2011 Oct;39(10):2135-40
pubmed: 21846925
Stem Cells Int. 2012;2012:691605
pubmed: 22363348
Equine Vet J. 2012 Jan;44(1):13-9
pubmed: 21496103
Front Vet Sci. 2020 Jun 26;7:323
pubmed: 32671108
Birth Defects Res C Embryo Today. 2012 Sep;96(3):258-70
pubmed: 23109321
Equine Vet J. 2012 May;44(3):371-5
pubmed: 22486548
Eur Cell Mater. 2018 Nov 6;36:218-230
pubmed: 30398288
Ther Adv Musculoskelet Dis. 2013 Apr;5(2):77-94
pubmed: 23641259
Vet Radiol Ultrasound. 2018 Nov;59(6):721-736
pubmed: 30136364
Vet Clin North Am Equine Pract. 2010 Apr;26(1):141-53
pubmed: 20381743
Regen Med. 2008 Jan;3(1):1-5
pubmed: 18154457
Stem Cells Int. 2014;2014:340257
pubmed: 25132856
Arthritis Res Ther. 2013;15(6):223
pubmed: 24321104
Vet Surg. 2000 May-Jun;29(3):218-26
pubmed: 10871223
Vet Immunol Immunopathol. 2013 Jun 15;153(3-4):217-26
pubmed: 23521925
Am J Vet Res. 2016 Aug;77(8):898-905
pubmed: 27463555
Dev Dyn. 1998 Jul;212(3):385-93
pubmed: 9671942
Equine Vet J. 2018 Jan;50(1):133-140
pubmed: 28667767
Osteoarthritis Cartilage. 2013 Jan;21(1):16-21
pubmed: 23194896
Can Vet J. 2015 Aug;56(8):831-8
pubmed: 26246629
Stem Cell Res Ther. 2020 Feb 7;11(1):52
pubmed: 32028995
J Equine Sci. 2016;27(3):81-97
pubmed: 27703403
Equine Vet J. 2012 Jan;44(1):101-6
pubmed: 21668494
Am J Vet Res. 2007 Oct;68(10):1095-105
pubmed: 17916017
BMC Musculoskelet Disord. 2013 Nov 17;14:324
pubmed: 24237933
Semin Cell Dev Biol. 2017 Jan;61:71-79
pubmed: 27521522
Vet Q. 2014;34(2):92-7
pubmed: 25072527
Vet Rec. 2010 Oct 30;167(18):690-4
pubmed: 21257484
Am J Sports Med. 2013 Sep;41(9):2158-66
pubmed: 23831891
Bone Joint Res. 2012 Nov 01;1(11):297-309
pubmed: 23610661
Tissue Eng Part A. 2011 May;17(9-10):1425-36
pubmed: 21247341
BMC Vet Res. 2018 Aug 17;14(1):241
pubmed: 30119668
Prev Vet Med. 2013 Nov 1;112(3-4):387-400
pubmed: 24125697
Prev Vet Med. 2008 Feb 1;83(2):130-43
pubmed: 17681389
FASEB J. 2019 Dec;33(12):14337-14353
pubmed: 31665925
Nat Rev Rheumatol. 2016 Apr;12(4):243-9
pubmed: 26729461
J Am Vet Med Assoc. 2013 Jan 1;242(1):93-8
pubmed: 23234287
Stem Cells Dev. 2018 Sep 1;27(17):1147-1160
pubmed: 29978736
Stem Cell Res Ther. 2019 Jun 18;10(1):181
pubmed: 31215490
Biomed Pharmacother. 2018 Dec;108:476-485
pubmed: 30241051
ScientificWorldJournal. 2012;2012:793823
pubmed: 22500143
Arthritis Rheum. 2003 Dec;48(12):3464-74
pubmed: 14673997
Equine Vet J. 2006 May;38(3):246-51
pubmed: 16706280
Equine Vet J. 2012 Nov;44(6):738-40
pubmed: 23106625
Stem Cell Res Ther. 2019 Dec 18;10(1):394
pubmed: 31852535
Cell Tissue Res. 2019 Feb;375(2):329-344
pubmed: 30084022
Vet Comp Orthop Traumatol. 2021 Jan;34(1):59-67
pubmed: 32799311
Clin Sports Med. 1990 Jul;9(3):523-38
pubmed: 2199066
Int J Mol Sci. 2018 Feb 10;19(2):
pubmed: 29439436
Acta Orthop. 2016 Dec;87(sup363):6-14
pubmed: 27658487
Semin Cell Dev Biol. 2008 Oct;19(5):459-66
pubmed: 18692584
Toxicol Pathol. 2019 Nov 19;:192623319880469
pubmed: 31741428
Vet Clin North Am Equine Pract. 2010 Apr;26(1):103-14
pubmed: 20381739
Vet Comp Orthop Traumatol. 2013;26(6):453-60
pubmed: 24080668
Equine Vet J. 2007 Jan;39(1):42-7
pubmed: 17228594
Cytotherapy. 2013 Aug;15(8):1011-20
pubmed: 23602577
Int J Mol Sci. 2017 Oct 02;18(10):
pubmed: 28974046
BMC Vet Res. 2014 Jan 10;10:11
pubmed: 24410888
Equine Vet J. 2016 Mar;48(2):152-8
pubmed: 25377505
Stem Cells. 2017 Feb;35(2):316-324
pubmed: 27888550
Eur Cell Mater. 2011 Feb 24;21:202-20
pubmed: 21351054
Am J Vet Res. 2014 Feb;75(2):141-51
pubmed: 24471750
Equine Vet J. 2011 Sep;43(5):516-21
pubmed: 21496084
Equine Vet J Suppl. 2006 Aug;(36):411-6
pubmed: 17402457
Equine Vet J. 2017 May;49(3):314-321
pubmed: 26582764
Ann Rheum Dis. 2008 Oct;67(10):1468-73
pubmed: 18178693
Res Vet Sci. 2018 Jun;118:423-430
pubmed: 29715649
Stem Cells Dev. 2013 Nov 15;22(22):3015-24
pubmed: 23795963
Vet J. 2016 Aug;214:61-71
pubmed: 27387728
J Orthop Res. 2020 Dec;38(12):2539-2550
pubmed: 32589800
Vet Surg. 2012 Oct;41(7):773-83
pubmed: 22804243
NPJ Regen Med. 2018 Feb 23;3:6
pubmed: 29507774
Equine Vet J. 2011 Jan;43(1):30-6
pubmed: 21143631
Res Vet Sci. 2020 Oct;132:407-415
pubmed: 32768869
Vet J. 2012 Apr;192(1):57-64
pubmed: 21550271
Vet Surg. 2015 Nov;44(8):1036-41
pubmed: 26455917
Res Vet Sci. 2015 Aug;101:140-3
pubmed: 26267104
Res Vet Sci. 2019 Oct;126:38-44
pubmed: 31430578
Stem Cells Int. 2018 Jun 6;2018:1073705
pubmed: 29977305
J Anim Sci. 2015 Mar;93(3):871-8
pubmed: 26020865
J Am Vet Med Assoc. 2020 Sep 15;257(6):642-647
pubmed: 32856998
Vet Surg. 2019 Aug;48(6):956-965
pubmed: 31199028
Mediators Inflamm. 2015;2015:435783
pubmed: 25814789
Vet J. 2004 Mar;167(2):129-42
pubmed: 14975387
Anesthesiology. 2014 Nov;121(5):1099-121
pubmed: 25211170
Front Physiol. 2018 Jun 25;9:706
pubmed: 29988615
Am J Vet Res. 2007 Mar;68(3):290-6
pubmed: 17331019
J Clin Med. 2019 May 14;8(5):
pubmed: 31091732
Eur Cell Mater. 2013 Sep 23;26:150-70
pubmed: 24057873
Equine Vet J. 2017 Jul;49(4):539-544
pubmed: 27862236
Best Pract Res Clin Obstet Gynaecol. 2004 Dec;18(6):893-908
pubmed: 15582545
Blood. 2015 Jan 15;125(3):419-20
pubmed: 25593329
Biomaterials. 2018 Feb;156:16-27
pubmed: 29182933
J Cell Biochem. 2006 Aug 1;98(5):1076-84
pubmed: 16619257
Cells. 2020 Jun 11;9(6):
pubmed: 32545382
J Am Vet Med Assoc. 2016 Oct 15;249(8):931-939
pubmed: 27700272
Cell Death Dis. 2013 Nov 07;4:e911
pubmed: 24201810
Vet Immunol Immunopathol. 2018 Jun;200:1-6
pubmed: 29776607
Int J Mol Sci. 2017 Oct 11;18(10):
pubmed: 29019941
Cell Med. 2012;4(1):1-11
pubmed: 23152950
Stem Cells. 2014 May;32(5):1254-66
pubmed: 24449146
BMC Vet Res. 2017 Jan 5;13(1):7
pubmed: 28056978
Philos Trans R Soc Lond B Biol Sci. 2004 May 29;359(1445):839-50
pubmed: 15293811
Arthritis Res Ther. 2010;12(3):R114
pubmed: 20537160
Vet J. 2011 Mar;187(3):325-9
pubmed: 20089426
Equine Vet J. 2015 May;47(3):319-25
pubmed: 24773596
Gene Ther. 2002 Jan;9(1):12-20
pubmed: 11850718
Stem Cell Res Ther. 2014 Jan 24;5(1):13
pubmed: 24461709
Nat Clin Pract Rheumatol. 2007 Jul;3(7):391-9
pubmed: 17599073
Bone. 2016 Apr;85:81-90
pubmed: 26812612
Nat Rev Rheumatol. 2010 Nov;6(11):625-35
pubmed: 20924410
Arthritis Rheum. 2012 Jun;64(6):1697-707
pubmed: 22392533
Stem Cell Res Ther. 2015 Jun 26;6:126
pubmed: 26113022
BMC Vet Res. 2019 Aug 14;15(1):292
pubmed: 31412868
Stem Cell Res Ther. 2014 Feb 21;5(1):25
pubmed: 24559797
J Equine Vet Sci. 2020 Sep;92:103178
pubmed: 32797800
J Am Vet Med Assoc. 2005 Nov 15;227(10):1646-50
pubmed: 16313045
Equine Vet J. 2012 Sep;44(5):594-9
pubmed: 22212017
Tierarztl Prax Ausg G Grosstiere Nutztiere. 2015;43(2):97-104
pubmed: 25782443
J Orthop Translat. 2015 Mar 11;3(2):71-77
pubmed: 30035042
BMC Vet Res. 2020 Jun 8;16(1):181
pubmed: 32513154
Osteoarthritis Cartilage. 2014 Aug;22(8):1167-75
pubmed: 24911520
Vet Clin North Am Equine Pract. 2011 Aug;27(2):299-314
pubmed: 21872760
Vet J. 2013 Oct;198(1):57-69
pubmed: 24070987
Gene Ther. 2010 Jun;17(6):733-44
pubmed: 20220786
Tissue Eng Part B Rev. 2017 Feb;23(1):44-58
pubmed: 27596929
Stem Cells Dev. 2019 Nov 1;28(21):1413-1423
pubmed: 31507234
Am J Vet Res. 2016 Jul;77(7):779-88
pubmed: 27347833
J Am Vet Med Assoc. 2002 Oct 1;221(7):1014-8
pubmed: 12369680