Preprocedural Pool Testing Strategy for Dentistry during the COVID-19 Pandemic.

clinical laboratory techniques coronavirus infections/diagnosis economics pandemics polymerase chain reaction specimen handling

Journal

JDR clinical and translational research
ISSN: 2380-0852
Titre abrégé: JDR Clin Trans Res
Pays: United States
ID NLM: 101684997

Informations de publication

Date de publication:
04 2021
Historique:
pubmed: 23 1 2021
medline: 19 3 2021
entrez: 22 1 2021
Statut: ppublish

Résumé

Aerosol-generating procedures (AGPs) put the dental health care professionals (DHCPs) at a greater risk for acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In late June 2020, the Centers for Disease Control and Prevention advised elective dental procedures provision to asymptomatic patients while mandating strict infection control protocol and suggested the use of preprocedural testing as an adjunct. A cost-effective method for mass preprocedural testing is pool testing, which has specificity and sensitivity similar to polymerase chain reaction. This article aims to assess the outcomes and utility of incorporating preprocedural testing protocol for SARS-CoV-2 in dental clinics before providing AGPs. The patients who were recommended AGPs where rubber dam placement was not possible were advised to undergo preprocedural testing for SARS-CoV-2. Pool testing strategy was employed, and patients were asked to get tested 48 h before the day of the procedure. Out of a total of 1,000 patients, who presented from June 2020 to late July 2020, 464 were recommended dental procedures. In 194 of 464, AGPs could not be performed under rubber dam isolation; therefore, the patients were advised to get a preprocedural pool test. In total, 111 patients deferred the procedure and testing. Out of 83 who got tested, 7 were positive for SARS-CoV-2, 5 of whom were tested in early June 2020 and 2 in late July 2020. Pool testing within its limitations can be a useful preprocedure test in asymptomatic low-risk patients for AGP in dentistry, especially when the disease prevalence is low or moderate (<10%). It has the potential of reducing testing costs significantly while conserving reagent and other resources. Preprocedure testing, however, also gives rise to certain ethical concerns that also need to be addressed. The results of this study can be used by clinicians when deciding which preprocedure testing approach they wish to use when performing aerosol-generating procedures in asymptomatic patients with consideration of cost sensitivity and specificity values.

Identifiants

pubmed: 33478305
doi: 10.1177/2380084421989693
pmc: PMC7871048
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

139-144

Références

Clin Infect Dis. 2020 Nov 19;71(16):2027-2034
pubmed: 32221519
J Med Virol. 2020 Oct;92(10):2193-2199
pubmed: 32401343
Br Dent J. 2020 Jun;228(11):811
pubmed: 32541701
Int Endod J. 2020 Aug;53(8):1062-1067
pubmed: 32357257
Travel Med Infect Dis. 2020 Sep-Oct;37:101673
pubmed: 32311437
N Engl J Med. 2020 May 21;382(21):2049-2055
pubmed: 32202722
JAMA. 2020 May 19;323(19):1967-1969
pubmed: 32250394
Nature. 2021 Jan;589(7841):276-280
pubmed: 33086375
BMJ. 2020 May 12;369:m1808
pubmed: 32398230
J Clin Microbiol. 2004 Apr;42(4):1471-6
pubmed: 15070991
J Dent. 2020 Aug;99:103387
pubmed: 32473182
Clin Infect Dis. 2020 Jul 28;71(15):799-806
pubmed: 32271376
Spec Care Dentist. 2020 Jul;40(4):395-396
pubmed: 32501576
Oral Dis. 2021 Apr;27 Suppl 3:655-664
pubmed: 32428372
J Infect. 2020 Jul;81(1):e28-e32
pubmed: 32283141
Am J Clin Pathol. 2020 May 5;153(6):715-718
pubmed: 32304208
Lancet Infect Dis. 2021 Apr;21(4):e73
pubmed: 32791041
Spec Care Dentist. 2020 Sep;40(5):431-436
pubmed: 32815633
Ann Intern Med. 2020 May 05;172(9):577-582
pubmed: 32150748

Auteurs

F Umer (F)

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

A Arif (A)

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH