Impact of Prematurity on the Tissue Properties of the Neonatal Brain Stem: A Quantitative MR Approach.
Journal
AJNR. American journal of neuroradiology
ISSN: 1936-959X
Titre abrégé: AJNR Am J Neuroradiol
Pays: United States
ID NLM: 8003708
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
06
06
2020
accepted:
14
10
2020
pubmed:
23
1
2021
medline:
18
5
2021
entrez:
22
1
2021
Statut:
ppublish
Résumé
Preterm birth interferes with regular brain development. The aim of this study was to investigate the impact of prematurity on the physical tissue properties of the neonatal brain stem using a quantitative MR imaging approach. A total of 55 neonates (extremely preterm [ There were significant differences between premature and term infants for T1 relaxation time (midbrain: Quantitative MR parameters allow preterm and term neonates to be differentiated. T1 and T2 relaxation time metrics of the midbrain allow differentiation between the different stages of prematurity. SyMRI allows for a quantitative assessment of incomplete brain maturation by providing tissue-specific properties while not exceeding a clinically acceptable imaging time.
Sections du résumé
BACKGROUND AND PURPOSE
Preterm birth interferes with regular brain development. The aim of this study was to investigate the impact of prematurity on the physical tissue properties of the neonatal brain stem using a quantitative MR imaging approach.
MATERIALS AND METHODS
A total of 55 neonates (extremely preterm [
RESULTS
There were significant differences between premature and term infants for T1 relaxation time (midbrain:
CONCLUSIONS
Quantitative MR parameters allow preterm and term neonates to be differentiated. T1 and T2 relaxation time metrics of the midbrain allow differentiation between the different stages of prematurity. SyMRI allows for a quantitative assessment of incomplete brain maturation by providing tissue-specific properties while not exceeding a clinically acceptable imaging time.
Identifiants
pubmed: 33478940
pii: ajnr.A6945
doi: 10.3174/ajnr.A6945
pmc: PMC7959430
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
581-589Informations de copyright
© 2021 by American Journal of Neuroradiology.
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