Prevalence estimates of dementia in older adults in rural Kilimanjaro 2009-2010 and 2018-2019: is there evidence of changing prevalence?


Journal

International journal of geriatric psychiatry
ISSN: 1099-1166
Titre abrégé: Int J Geriatr Psychiatry
Pays: England
ID NLM: 8710629

Informations de publication

Date de publication:
06 2021
Historique:
received: 15 12 2020
accepted: 27 12 2020
pubmed: 23 1 2021
medline: 3 6 2021
entrez: 22 1 2021
Statut: ppublish

Résumé

Although limited, existing epidemiological data on dementia in sub-Saharan Africa indicate that prevalence may be increasing; contrasting with recent decreases observed in high-income countries. We have previously reported the age-adjusted prevalence of dementia in rural Tanzania in 2009-2010 as 6.4% (95% confidence interval [CI] 4.9-7.9) in individuals aged ≥70 years. We aimed to repeat a community-based dementia prevalence study in the same setting to assess whether prevalence has changed. This was a two-phase door-to-door community-based cross-sectional survey in Kilimanjaro, Tanzania. In Phase I, trained primary health workers screened all consenting individuals aged ≥60 years from 12 villages using previously validated, locally developed, tools (IDEA cognitive screen and IDEA-Instrumental Activities of Daily Living questionnaire). Screening was conducted using a mobile digital application (app) on a hand-held tablet. In Phase II, a stratified sample of those identified in Phase I were clinically assessed using the DSM-5 criteria and diagnoses subsequently confirmed by consensus panel. Of 3011 people who consented, 424 screened positive for probable dementia and 227 for possible dementia. During clinical assessment in Phase II, 105 individuals met DSM-5 dementia criteria. The age-adjusted prevalence of dementia was 4.6% (95% CI 2.9-6.4) in those aged ≥60 years and 8.9% (95% CI 6.1-11.8) in those aged ≥70 years. Prevalence rates increased significantly with age. The prevalence of dementia in this rural Tanzanian population appears to have increased since 2010, although not significantly. Dementia is likely to become a significant health burden in this population as demographic transition continues.

Identifiants

pubmed: 33480089
doi: 10.1002/gps.5498
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

950-959

Subventions

Organisme : Department of Health
Pays : United Kingdom
Organisme : Department of Health
ID : 16/137/62
Pays : United Kingdom

Informations de copyright

© 2021 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd.

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Auteurs

Marcella Yoseph (M)

Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Stella-Maria Paddick (SM)

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

William K Gray (WK)

Department of Medicine, Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, North Shields, UK.

Damas Andrea (D)

Mirembe National Hospital, Dodoma, Tanzania.

Robyn Barber (R)

Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Aoife Colgan (A)

Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Catherine Dotchin (C)

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Department of Medicine, Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, North Shields, UK.

Sarah Urasa (S)

Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Aloyce Kisoli (A)

Kilimanjaro Christian Medical University College, Moshi, Tanzania.

John Kissima (J)

Hai District Hospital, Boman'gombe, Kilimanjaro, Tanzania.

Irene Haule (I)

Hai District Hospital, Boman'gombe, Kilimanjaro, Tanzania.

Jane Rogathi (J)

Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Ssenku Safic (S)

Mount Meru Hospital, Arusha, Tanzania.

Declare Mushi (D)

Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Louise Robinson (L)

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

Richard W Walker (RW)

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Department of Medicine, Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital, North Shields, UK.

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