[Quality assessment of radical cystectomy-opportunities, risks, challenges].
Qualitätsparameter bei der radikalen Zystektomie – Chancen, Risiken, Herausforderungen.
Bladder cancer
Quality assessment
Quality of life
Treatment outcome
Urinary diversion
Journal
Der Urologe. Ausg. A
ISSN: 1433-0563
Titre abrégé: Urologe A
Pays: Germany
ID NLM: 1304110
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
accepted:
18
12
2020
pubmed:
23
1
2021
medline:
20
2
2021
entrez:
22
1
2021
Statut:
ppublish
Résumé
Radical cystectomy (RC) is the standard treatment for nonmetastatic muscle-invasive urothelial carcinoma of the urinary bladder. It is associated with relevant morbidity and mortality. After RC, the 5‑year overall survival rate is approximately 60%. In the context of the present work, quality parameters of RC divided into oncological/functional criteria and freedom from complications are identified and summarized. A PubMed search was performed. In addition to early criteria such as negative surgical margins, performance of pelvic lymphadenectomy, creation of a continent urinary diversion or preservation of sexual function, long-term criteria were identified such as the absence of higher-grade postoperative complications, recurrence-free survival and the preservation of health-related quality of life. The early criteria are suitable for individualized therapy planning, whereas the long-term criteria can be used for quality monitoring. Die radikale Zystektomie (RC) ist die Standardbehandlung des nicht-metastasierten muskelinvasiven Urothelkarzinoms der Harnblase. Sie ist mit einer relevanten Morbidität und Mortalität assoziiert. Nach RC liegt die 5‑Jahres-Gesamtüberlebensrate bei ungefähr 60 %. Im Rahmen der vorliegenden Arbeit sollen Qualitätsparameter der RC identifiziert und unterteilt in onkologische/funktionelle Ergebnisse sowie Komplikationsfreiheit zusammengefasst werden. Es wurde eine PubMed-Recherche durchgeführt. Neben Frühkriterien wie dem Erreichen eines negativen Resektionsrandes, der Durchführung einer Lymphadenektomie, der Anlage einer kontinenten Harnableitung oder dem Erhalt der Sexualfunktion konnten auch Langzeitkriterien wie das Ausbleiben höhergradiger postoperativer Komplikationen, die Rezidivfreiheit und der Erhalt der Lebensqualität identifiziert werden. Die Frühkriterien eignen sich zur individualisierten Therapieplanung im Rahmen der Patientenberatung, wohingegen die Langzeitkriterien zum Qualitätsmonitoring genutzt werden können.
Autres résumés
Type: Publisher
(ger)
Die radikale Zystektomie (RC) ist die Standardbehandlung des nicht-metastasierten muskelinvasiven Urothelkarzinoms der Harnblase. Sie ist mit einer relevanten Morbidität und Mortalität assoziiert. Nach RC liegt die 5‑Jahres-Gesamtüberlebensrate bei ungefähr 60 %. Im Rahmen der vorliegenden Arbeit sollen Qualitätsparameter der RC identifiziert und unterteilt in onkologische/funktionelle Ergebnisse sowie Komplikationsfreiheit zusammengefasst werden. Es wurde eine PubMed-Recherche durchgeführt. Neben Frühkriterien wie dem Erreichen eines negativen Resektionsrandes, der Durchführung einer Lymphadenektomie, der Anlage einer kontinenten Harnableitung oder dem Erhalt der Sexualfunktion konnten auch Langzeitkriterien wie das Ausbleiben höhergradiger postoperativer Komplikationen, die Rezidivfreiheit und der Erhalt der Lebensqualität identifiziert werden. Die Frühkriterien eignen sich zur individualisierten Therapieplanung im Rahmen der Patientenberatung, wohingegen die Langzeitkriterien zum Qualitätsmonitoring genutzt werden können.
Identifiants
pubmed: 33481063
doi: 10.1007/s00120-020-01439-8
pii: 10.1007/s00120-020-01439-8
doi:
Types de publication
Journal Article
Review
Langues
ger
Sous-ensembles de citation
IM
Pagination
151-161Références
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