Pharmacist's knowledge regarding the management of overactive bladder in elderly women.

Anticholinergic burden Anticholinergic load Anticholinergic medication Knowledge Overactive bladder Pharmacists

Journal

European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 09 12 2020
revised: 12 01 2021
accepted: 13 01 2021
pubmed: 24 1 2021
medline: 15 5 2021
entrez: 23 1 2021
Statut: ppublish

Résumé

Anticholinergic drugs are the mainstay treatment of OAB. Anticholinergic load is the cumulative effect of taking anticholinergic medication. Recent evidence suggests that in the elderly this can have a detrimental affect, with the potential to develop dementia. A previous study found that knowledge of anticholinergic load was lacking in our healthcare professionals. The aim of this study was to assess knowledge of pharmacists, who in the UK have the potential where qualified to prescribe as well as dispense. A questionnaire was formulated based on the previous study. It was sent out to 418 pharmacists from; a south London hospital trust, a south London clinical commissioning group and United Kingdom Clinical Pharmacists Association. Seventy-five pharmacists completed the questionnaire. Solifenacin and tolterodine was the most popular drug prescribed in the elderly without dementia, whilst mirabegron was the most popular in the elderly with dementia. One pharmacist suggested using oxybutynin. Sixty-two percent discuss anticholinergic load with the patients, 40 % advice prescribers and 42 % consider anticholinergic load when dispensing the drug. Fifteen percent have had patients report confusion/memory loss. Thirty percent know how to assess anticholinergic load. Only 15 % felt dementia was a concern with anticholinergic drugs. Worryingly, 54 % though mirabegron exerted anticholinergic effects. This is the first study looking at pharmacist knowledge on the use of anticholinergic medication for OAB in elderly women. Knowledge amongst all healthcare professionals including pharmacists is lacking and needs to be improved.

Identifiants

pubmed: 33485264
pii: S0301-2115(21)00033-6
doi: 10.1016/j.ejogrb.2021.01.021
pii:
doi:

Substances chimiques

Tolterodine Tartrate 5T619TQR3R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

269-272

Informations de copyright

Crown Copyright © 2021. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare no conflict of interest.

Auteurs

George Araklitis (G)

Department of Urogynaecology, King's College Hospital, London, UK. Electronic address: george.araklitis@nhs.net.

Angie Rantell (A)

Department of Urogynaecology, King's College Hospital, London, UK.

Georgina Baines (G)

Department of Urogynaecology, King's College Hospital, London, UK.

Richard Flint (R)

Department of Urogynaecology, King's College Hospital, London, UK.

Dudley Robinson (D)

Department of Urogynaecology, King's College Hospital, London, UK.

Linda Cardozo (L)

Department of Urogynaecology, King's College Hospital, London, UK.

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Classifications MeSH