Reduction in epistaxis and emergency department visits in patients taking warfarin after implementation of an education program.


Journal

Thrombosis research
ISSN: 1879-2472
Titre abrégé: Thromb Res
Pays: United States
ID NLM: 0326377

Informations de publication

Date de publication:
03 2021
Historique:
received: 27 08 2020
revised: 06 01 2021
accepted: 08 01 2021
pubmed: 25 1 2021
medline: 22 6 2021
entrez: 24 1 2021
Statut: ppublish

Résumé

Anticoagulated patients are often seen unnecessarily in the emergency department (ED) for epistaxis, leading to increased healthcare costs. Patients are often unaware of preventative and management techniques for handling epistaxis in the home. In 2016, the Michigan Anticoagulation Quality Improvement Initiative (MAQI Of the 4473 patients included, 2634 (58.9%) initiated warfarin in the pre-implementation phase and 1839 (41.1%) initiated warfarin in the post-implementation phase. The post-implementation cohort had a lower overall epistaxis rate (13.4 vs 10.4 per 100 patient-year, pre- vs. post-implementation; p = 0.029), a lower epistaxis-related ED visit rate (5.6 vs. 3.1 per 100 patient-year; p = 0.003), and a lower proportion of nosebleeds that led to an ED visit (42% vs. 30%; p = 0.032). After controlling for antiplatelet use, renal disease, and time in therapeutic range, both cohorts were equally likely to have nosebleeds (RR 0.77, 95% CI: 0.58-1.02); however, the post-implementation cohort was less likely to visit the ED for epistaxis (RR 0.52, 95% CI: 0.32-0.84). An epistaxis education program was associated with a reduction in epistaxis-related ED visits among warfarin-treated patients.

Sections du résumé

BACKGROUND
Anticoagulated patients are often seen unnecessarily in the emergency department (ED) for epistaxis, leading to increased healthcare costs. Patients are often unaware of preventative and management techniques for handling epistaxis in the home.
METHODS
In 2016, the Michigan Anticoagulation Quality Improvement Initiative (MAQI
RESULTS
Of the 4473 patients included, 2634 (58.9%) initiated warfarin in the pre-implementation phase and 1839 (41.1%) initiated warfarin in the post-implementation phase. The post-implementation cohort had a lower overall epistaxis rate (13.4 vs 10.4 per 100 patient-year, pre- vs. post-implementation; p = 0.029), a lower epistaxis-related ED visit rate (5.6 vs. 3.1 per 100 patient-year; p = 0.003), and a lower proportion of nosebleeds that led to an ED visit (42% vs. 30%; p = 0.032). After controlling for antiplatelet use, renal disease, and time in therapeutic range, both cohorts were equally likely to have nosebleeds (RR 0.77, 95% CI: 0.58-1.02); however, the post-implementation cohort was less likely to visit the ED for epistaxis (RR 0.52, 95% CI: 0.32-0.84).
CONCLUSION
An epistaxis education program was associated with a reduction in epistaxis-related ED visits among warfarin-treated patients.

Identifiants

pubmed: 33486320
pii: S0049-3848(21)00016-5
doi: 10.1016/j.thromres.2021.01.007
pii:
doi:

Substances chimiques

Warfarin 5Q7ZVV76EI

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

119-122

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Julian Neshewat (J)

University of Michigan, Ann Arbor, MI.

Amanda Wasserman (A)

University of Michigan, Ann Arbor, MI.

Constantina Alexandris-Souphis (C)

University of Michigan, Ann Arbor, MI.

Brian Haymart (B)

University of Michigan, Ann Arbor, MI.

Delaney Feldeisen (D)

University of Michigan, Ann Arbor, MI.

Xiaowen Kong (X)

University of Michigan, Ann Arbor, MI.

Rebecca S Harvey (RS)

University of Michigan, Ann Arbor, MI.

Melissa Pynnonen (M)

University of Michigan, Ann Arbor, MI.

James B Froehlich (JB)

University of Michigan, Ann Arbor, MI.

Eva Kline-Rogers (E)

University of Michigan, Ann Arbor, MI.

Geoffrey D Barnes (GD)

University of Michigan, Ann Arbor, MI. Electronic address: gbarnes@umich.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH