Lung Assessment with Point-of-Care Ultrasound in Respiratory Coronavirus Disease (COVID-19): A Prospective Cohort Study.


Journal

Ultrasound in medicine & biology
ISSN: 1879-291X
Titre abrégé: Ultrasound Med Biol
Pays: England
ID NLM: 0410553

Informations de publication

Date de publication:
04 2021
Historique:
received: 24 09 2020
revised: 16 12 2020
accepted: 17 12 2020
pubmed: 26 1 2021
medline: 12 3 2021
entrez: 25 1 2021
Statut: ppublish

Résumé

Lung ultrasound (LUS) has shown promising diagnostic potential in different pulmonary conditions. We evaluated the diagnostic accuracy of LUS for pulmonary COVID-19. In this prospective cohort study at a Swiss tertiary care center, patients hospitalized with suspected COVID-19 were scanned using a 12-zone protocol. Association of a summation score (0-36 points) with the final diagnosis was tested using the area under the receiver operating characteristic curve and sensitivity and specificity at different cutoff points. Of the 49 participants, 11 (22%) were later diagnosed with COVID-19. LUS score showed excellent diagnostic performance, with an odds ratio of 1.30 per point (95% confidence interval [CI], 1.09-1.54, p = 0.003) and an area under the curve of 0.85 (95% CI, 0.71-0.99). At a cutoff of 8/36 points, 10 of 11 participants later diagnosed with COVID-19 were correctly predicted (sensitivity 91%, 95% CI, 59%-100%), and 29 of the 38 who were not diagnosed with COVID-19 were correctly ruled out (specificity 76%, 95% CI, 60%-89%). LUS demonstrated promising discriminatory potential in people hospitalized with suspected COVID-19.

Identifiants

pubmed: 33487473
pii: S0301-5629(20)30576-7
doi: 10.1016/j.ultrasmedbio.2020.12.021
pmc: PMC7834656
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

896-901

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.

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Auteurs

Victor Speidel (V)

Department of Infectious Diseases and Hospital Hygiene, Kantonsspital Aarau, Aarau, Switzerland; University Clinic of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland; Department of Emergency Medicine, Oberaargau Regional Hospital, Langenthal, Switzerland. Electronic address: v.speidel@sro.ch.

Anna Conen (A)

Department of Infectious Diseases and Hospital Hygiene, Kantonsspital Aarau, Aarau, Switzerland; University Clinic of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland.

Valentin Gisler (V)

University Clinic of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland; Institute for Laboratory Medicine, Kantonsspital Aarau, Aarau, Switzerland.

Christoph A Fux (CA)

Department of Infectious Diseases and Hospital Hygiene, Kantonsspital Aarau, Aarau, Switzerland; University Clinic of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland.

Sebastian Haubitz (S)

Department of Infectious Diseases and Hospital Hygiene, Kantonsspital Aarau, Aarau, Switzerland; University Clinic of Internal Medicine, Kantonsspital Aarau, Aarau, Switzerland.

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