Factors Associated with the Clinical Course of Vitreomacular Traction.


Journal

Journal of ophthalmology
ISSN: 2090-004X
Titre abrégé: J Ophthalmol
Pays: United States
ID NLM: 101524199

Informations de publication

Date de publication:
2020
Historique:
received: 02 08 2020
revised: 05 11 2020
accepted: 13 12 2020
entrez: 25 1 2021
pubmed: 26 1 2021
medline: 26 1 2021
Statut: epublish

Résumé

To analyze the optical coherence tomography (OCT) characteristics as well as the clinical and demographic features to investigate their possible role to the course of vitreomacular traction syndrome. The inclusion criteria were vitreomacular adhesion with traction causing distortion of the retinal architecture, with or without the presence of an epiretinal membrane, regardless of the size of the adhesion; age >18 years; follow-up of at least three months; and adequate quality OCT scan. Measurements of foveal thickness, average macular thickness, macular volume, maximum vertical and horizontal vitreomacular adhesion, nasal and temporal angles of traction, hyaloid hyperreflectivity, the presence of an epiretinal membrane (ERM), and cone outer segment tips detachment were obtained. 150 eyes were included in the analysis. 36 eyes (24%) developed complete resolution at the last visit, 19 eyes (12.7%) formed a full-thickness macular hole, and 95 eyes (63.3%) showed no resolution of the traction. Better BCVA at the first visit was associated with an increased likelihood of resolution of the VMT, but increasing age, CMT, and BCVA in the end of the follow-up was associated with a reduction in the likelihood of resolving. Of the other variables that were studied, no statistical significant predictors were identified. Better BCVA in the first visit was associated with an increased likelihood of resolution of the VMT that occurred in 24% of our cases. Other factors such as the vertical area of adhesion and the angle of adhesion were not identified as prognostic factors affecting the clinical course of the disease.

Sections du résumé

BACKGROUND BACKGROUND
To analyze the optical coherence tomography (OCT) characteristics as well as the clinical and demographic features to investigate their possible role to the course of vitreomacular traction syndrome.
METHODS METHODS
The inclusion criteria were vitreomacular adhesion with traction causing distortion of the retinal architecture, with or without the presence of an epiretinal membrane, regardless of the size of the adhesion; age >18 years; follow-up of at least three months; and adequate quality OCT scan. Measurements of foveal thickness, average macular thickness, macular volume, maximum vertical and horizontal vitreomacular adhesion, nasal and temporal angles of traction, hyaloid hyperreflectivity, the presence of an epiretinal membrane (ERM), and cone outer segment tips detachment were obtained.
RESULTS RESULTS
150 eyes were included in the analysis. 36 eyes (24%) developed complete resolution at the last visit, 19 eyes (12.7%) formed a full-thickness macular hole, and 95 eyes (63.3%) showed no resolution of the traction. Better BCVA at the first visit was associated with an increased likelihood of resolution of the VMT, but increasing age, CMT, and BCVA in the end of the follow-up was associated with a reduction in the likelihood of resolving. Of the other variables that were studied, no statistical significant predictors were identified.
CONCLUSIONS CONCLUSIONS
Better BCVA in the first visit was associated with an increased likelihood of resolution of the VMT that occurred in 24% of our cases. Other factors such as the vertical area of adhesion and the angle of adhesion were not identified as prognostic factors affecting the clinical course of the disease.

Identifiants

pubmed: 33489349
doi: 10.1155/2020/9457670
pmc: PMC7803219
doi:

Types de publication

Journal Article

Langues

eng

Pagination

9457670

Informations de copyright

Copyright © 2020 Petros Petrou et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Petros Petrou (P)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Evangelia Chalkiadaki (E)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Marie-Helene Errera (MH)

University of Pittsburg, Pittsburgh, PA, USA.

Sidath Liyanage (S)

Bristol Eye Hospital, Bristol, UK.

Louisa Wickham (L)

Moorfields Eye Hospital, London, UK.

Evangelia Papakonstantinou (E)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Aristotelis Karamaounas (A)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Menelaos Kanakis (M)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Ilias Georgalas (I)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Stylianos Kandarakis (S)

First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

David Charteris (D)

Moorfields Eye Hospital, London, UK.

Classifications MeSH