Single-stage 360° Reconstruction in a Case of Solitary Vertebral Plasmacytoma of L3 vertebra - A Case Report.
360°
Plasma cell dyscrasias
fusion spine surgery
solitary plasmacytoma
Journal
Journal of orthopaedic case reports
ISSN: 2250-0685
Titre abrégé: J Orthop Case Rep
Pays: India
ID NLM: 101641392
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
entrez:
25
1
2021
pubmed:
26
1
2021
medline:
26
1
2021
Statut:
ppublish
Résumé
Malignant bone tumors of the spine are extremely rare with an incidence of 0.05% of primary neoplasms. Solitary plasmacytoma of the vertebra accounts for about 30% of the total within this group. A 23-year-old female presented to spine clinic, with complaints of low back pain, deformity in lower back, and difficulty in walking for 3 months duration. Radiological investigations revealed destruction of L3 vertebra with soft-tissue mass around it. USG-guided biopsy from the lesion was suggestive of plasma cell dyscrasia. Routine blood investigations showed no abnormality. Urine myeloma profile and immunoelectrophoresis were done which were within normal limit and ruled out multiple myeloma. Due to the profound neurological deficit and existing instability, the patient underwent decompression, resection of tumor, anterior column reconstruction with cage, and instrumented posterior and posterolateral fusion (360° fusion) from L1-L5, before radiotherapy. The patient was subjected to 23 cycles of intensity-modulated radiotherapy and is doing good on subsequent follow-ups with good fusion. Solitary plasmacytoma of vertebra when associated with neurological deficit and/or instability should be treated with spinal stabilization surgery followed by radiotherapy to achieve good and overall predictable outcomes.
Identifiants
pubmed: 33489963
doi: 10.13107/jocr.2020.v10.i06.1860
pii: JOCR-10-23
pmc: PMC7815668
doi:
Types de publication
Case Reports
Langues
eng
Pagination
23-27Informations de copyright
Copyright: © Indian Orthopaedic Research Group.
Déclaration de conflit d'intérêts
Conflict of Interest: Nil
Références
Am J Hematol. 2008 Sep;83(9):702-7
pubmed: 18543343
Hematol Oncol. 1996 Sep;14(3):111-7
pubmed: 9119355
BMC Cancer. 2006 May 05;6:118
pubmed: 16677383
Haematologica. 2000 Jan;85(1):47-51
pubmed: 10629591
Am J Hematol. 2012 Jul;87(7):647-51
pubmed: 22549792
J Clin Orthop Trauma. 2015 Dec;6(4):259-64
pubmed: 26566340
Cancer. 1992 Mar 15;69(6):1513-7
pubmed: 1540888
Spinal Cord. 1998 Jul;36(7):470-5
pubmed: 9670382
ScientificWorldJournal. 2012;2012:895765
pubmed: 22654647
Int J Radiat Oncol Biol Phys. 2006 Jan 1;64(1):210-7
pubmed: 16229966
Cancer. 2011 Oct 1;117(19):4468-74
pubmed: 21437886
Br J Haematol. 2004 Mar;124(6):717-26
pubmed: 15009059
Iowa Orthop J. 2004;24:86-94
pubmed: 15296213
J Med Educ. 1953 Apr;28(4):19-23
pubmed: 13053128