Idarubicin-Gold Complex: From Crystal Growth to Gold Nanoparticles.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
19 Jan 2021
19 Jan 2021
Historique:
received:
14
09
2020
accepted:
29
10
2020
entrez:
25
1
2021
pubmed:
26
1
2021
medline:
26
1
2021
Statut:
epublish
Résumé
Idarubicin (IDA) is the analog of daunorubicin (DNR). The absence of the methoxy group at position 4 of IDA remarkably improved lipophilicity, which is responsible for extra cellular uptake, higher DNA-binding ability, and considerable cytotoxicity in correlation with doxorubicin (DOX) and DNR. In this paper, we conceived two principal objectives: we realized the crystal structure of IDA by X-ray diffraction measurements on single crystals at room temperature (monoclinic, space group
Identifiants
pubmed: 33490782
doi: 10.1021/acsomega.0c04501
pmc: PMC7818310
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1235-1245Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2021 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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