Investigating the association of polymorphisms of
ANKRD55 polymorphism
MMEL1 polymorphism
MS
PCR- RFLP
multiple sclerosis
Journal
The International journal of neuroscience
ISSN: 1563-5279
Titre abrégé: Int J Neurosci
Pays: England
ID NLM: 0270707
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
pubmed:
26
1
2021
medline:
17
9
2022
entrez:
25
1
2021
Statut:
ppublish
Résumé
Multiple sclerosis (MS) is an autoimmune neurological disability in which immune cells attack the myelin sheaths that protect nerve fibers. The pathogenesis of the disease involves both complex genetic effects as well as multifaceted gene-environment interactions. In the present study, we examined the association of two Single nucleotide polymorphisms (SNPs) in In this case-control study, 110 patients with MS and 110 matched healthy controls were enrolled. The Participants were genotyped for Our results did not show significant differences in allelic frequencies of two SNPs among cases and controls ( We could successfully replicate the association of
Identifiants
pubmed: 33491520
doi: 10.1080/00207454.2020.1860964
doi:
Substances chimiques
ANKRD55 protein, human
0
Carrier Proteins
0
MMEL1 protein, human
EC 3.4.24.11
Neprilysin
EC 3.4.24.11
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM