Investigating the association of polymorphisms of


Journal

The International journal of neuroscience
ISSN: 1563-5279
Titre abrégé: Int J Neurosci
Pays: England
ID NLM: 0270707

Informations de publication

Date de publication:
Oct 2022
Historique:
pubmed: 26 1 2021
medline: 17 9 2022
entrez: 25 1 2021
Statut: ppublish

Résumé

Multiple sclerosis (MS) is an autoimmune neurological disability in which immune cells attack the myelin sheaths that protect nerve fibers. The pathogenesis of the disease involves both complex genetic effects as well as multifaceted gene-environment interactions. In the present study, we examined the association of two Single nucleotide polymorphisms (SNPs) in In this case-control study, 110 patients with MS and 110 matched healthy controls were enrolled. The Participants were genotyped for Our results did not show significant differences in allelic frequencies of two SNPs among cases and controls ( We could successfully replicate the association of

Identifiants

pubmed: 33491520
doi: 10.1080/00207454.2020.1860964
doi:

Substances chimiques

ANKRD55 protein, human 0
Carrier Proteins 0
MMEL1 protein, human EC 3.4.24.11
Neprilysin EC 3.4.24.11

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1037-1042

Auteurs

Mahboobeh Yazdanpanah (M)

Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Nazanin Jalilian (N)

Department of Clinical Biochemistry, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Rasoul Abdollah Zadeh (R)

Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Mohammad Ali Sahraian (MA)

MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.

Mohammad Reza Noori-Daloii (MR)

Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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Classifications MeSH