[New technologies to unveil the role of brain glial cells].
De nouvelles techniques pour dévoiler le rôle des cellules gliales du cerveau.
Journal
Medecine sciences : M/S
ISSN: 1958-5381
Titre abrégé: Med Sci (Paris)
Pays: France
ID NLM: 8710980
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
entrez:
25
1
2021
pubmed:
26
1
2021
medline:
28
10
2021
Statut:
ppublish
Résumé
Brain function relies on complex interactions between neurons and different types of glial cells, such as astrocytes, microglia and oligodendrocytes. The relatively young field of "gliobiology" is thriving. Thanks to various technical innovations, it is now possible to address challenging biological questions on glial cells and unravel their multiple roles in brain function and dysfunction. De nouvelles techniques pour dévoiler le rôle des cellules gliales du cerveau. L’exécution des fonctions cérébrales requiert des interactions optimales entre les neurones et les différents types de cellules gliales (astrocytes, microglies et oligodendrocytes). Le domaine de la gliobiologie, qui s’intéresse aux cellules gliales, est en pleine expansion. Les innovations techniques permettent désormais d’aborder des questions biologiques complexes quant aux rôles de ces cellules dans le fonctionnement physiologique et pathologique du cerveau. Dans cette synthèse, nous décrivons comment certaines de ces avancées techniques nous ont permis d’en apprendre davantage sur les origines et les rôles fonctionnels des cellules gliales. Nous illustrons également comment ces techniques et les découvertes qui en ont découlé, peuvent être transposées en clinique et pourraient, dans un futur proche, offrir des nouvelles perspectives thérapeutiques.
Autres résumés
Type: Publisher
(fre)
De nouvelles techniques pour dévoiler le rôle des cellules gliales du cerveau.
Identifiants
pubmed: 33492220
doi: 10.1051/medsci/2020253
pii: msc200161
doi:
Types de publication
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
59-67Informations de copyright
© 2021 médecine/sciences – Inserm.
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