R-COMP versus R-CHOP as first-line therapy for diffuse large B-cell lymphoma in patients ≥60 years: Results of a randomized phase 2 study from the Spanish GELTAMO group.
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols
/ administration & dosage
Cyclophosphamide
/ administration & dosage
Doxorubicin
/ administration & dosage
Female
Humans
Lymphoma, Large B-Cell, Diffuse
/ drug therapy
Male
Middle Aged
Prednisone
/ administration & dosage
Prospective Studies
Retrospective Studies
Rituximab
/ administration & dosage
Treatment Outcome
Ventricular Function, Left
/ drug effects
Vincristine
/ administration & dosage
N-terminal pro-B-type natriuretic peptide
cardiotoxicity
diffuse large B-cell lymphoma
liposomal doxorubicin
troponin
Journal
Cancer medicine
ISSN: 2045-7634
Titre abrégé: Cancer Med
Pays: United States
ID NLM: 101595310
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
28
04
2020
revised:
30
11
2020
accepted:
24
12
2020
pubmed:
26
1
2021
medline:
6
8
2021
entrez:
25
1
2021
Statut:
ppublish
Résumé
The use of non-pegylated liposomal doxorubicin (Myocet
Identifiants
pubmed: 33492774
doi: 10.1002/cam4.3730
pmc: PMC7926012
doi:
Substances chimiques
R-CHOP protocol
0
Rituximab
4F4X42SYQ6
Vincristine
5J49Q6B70F
Doxorubicin
80168379AG
Cyclophosphamide
8N3DW7272P
Prednisone
VB0R961HZT
Banques de données
ClinicalTrials.gov
['NCT02012088']
Types de publication
Clinical Trial, Phase II
Comparative Study
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1314-1326Informations de copyright
© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.
Références
Semin Oncol. 2004 Dec;31(6 Suppl 13):5-15
pubmed: 15717735
Ann Oncol. 2010 Jul;21(7):1492-1499
pubmed: 20007997
Lancet Oncol. 2011 May;12(5):460-8
pubmed: 21482186
Circulation. 2004 Jun 8;109(22):2749-54
pubmed: 15148277
J Clin Oncol. 2001 Mar 1;19(5):1444-54
pubmed: 11230490
N Engl J Med. 2002 Jan 24;346(4):235-42
pubmed: 11807147
PLoS One. 2017 Nov 13;12(11):e0188025
pubmed: 29131861
Clin Oncol (R Coll Radiol). 2014 Oct;26(10):648-52
pubmed: 24929649
Clin Chem Lab Med. 2011 Sep 06;49(12):1937-48
pubmed: 21892906
Eur J Cancer. 2016 May;58:112-21
pubmed: 26990931
Heart Fail Clin. 2011 Jul;7(3):323-31
pubmed: 21749884
Clin Chem. 2005 Aug;51(8):1405-10
pubmed: 15932966
Drugs. 1998 Sep;56(3):385-403
pubmed: 9777314
Prog Cardiovasc Dis. 2010 Sep-Oct;53(2):121-9
pubmed: 20728699
Ann Oncol. 2003 Feb;14(2):277-81
pubmed: 12562656
Br J Cancer. 2002 Jun 5;86(11):1697-700
pubmed: 12087452
Hematol Oncol. 2007 Dec;25(4):198-203
pubmed: 17654614
Oncotarget. 2018 Aug 17;9(64):32383-32399
pubmed: 30190794
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):233-70
pubmed: 25712077
Oncology (Williston Park). 2002 Apr;16(4):490-502, 507-8; discussion 511-2, 514
pubmed: 12017536
J Clin Oncol. 2007 Feb 10;25(5):579-86
pubmed: 17242396
J Clin Oncol. 2004 Jul 1;22(13):2662-70
pubmed: 15226333
Lancet Oncol. 2008 Feb;9(2):105-16
pubmed: 18226581
Biometrics. 1973 Sep;29(3):579-84
pubmed: 4793138
Leuk Lymphoma. 2008 Jun;49(6):1081-6
pubmed: 18569635
Med Clin (Barc). 2010 Jan 30;134(2):72-5
pubmed: 19913261