Surfactant for the Treatment of ARDS in a Patient With COVID-19.
Antiviral Agents
/ administration & dosage
Biological Products
/ administration & dosage
COVID-19
/ blood
Critical Care
/ methods
Drug Monitoring
/ methods
Extracorporeal Membrane Oxygenation
/ methods
Humans
Hypoxia
/ etiology
Lung
/ diagnostic imaging
Male
Middle Aged
Oximetry
/ methods
Patient Positioning
/ methods
Pulmonary Surfactants
/ administration & dosage
Respiration, Artificial
/ methods
SARS-CoV-2
/ isolation & purification
Treatment Outcome
ARDS
COVID-19
surfactant
Journal
Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
09
07
2020
revised:
03
12
2020
accepted:
02
01
2021
pubmed:
26
1
2021
medline:
21
7
2021
entrez:
25
1
2021
Statut:
ppublish
Résumé
Patients with COVID-19 report severe respiratory symptoms consistent with ARDS. The clinical presentation of ARDS in COVID-19 is often atypical, as patients with COVID-19 exhibit a disproportionate hypoxemia compared with relatively preserved lung mechanics. This pattern is more similar to neonatal respiratory distress syndrome secondary to surfactant deficiency, which has been shown to benefit from exogenous surfactant. We present our experience with exogenous surfactant treatment in a patient with COVID-19 experiencing COVID-19-related ARDS. The patient responded with improved oxygenation, and we believe surfactant was the catalyst for the successful extubation and clinical improvement of the patient.
Identifiants
pubmed: 33493441
pii: S0012-3692(21)00100-8
doi: 10.1016/j.chest.2021.01.028
pmc: PMC7825915
pii:
doi:
Substances chimiques
Antiviral Agents
0
Biological Products
0
Pulmonary Surfactants
0
calfactant
Q4K217VGA9
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
e9-e12Informations de copyright
Copyright © 2021 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
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