COVID-19 and Gut Microbiota: A Potential Connection.
Immune system
Microbiota
Probiotic
SARS-CoV-2
Journal
Indian journal of clinical biochemistry : IJCB
ISSN: 0970-1915
Titre abrégé: Indian J Clin Biochem
Pays: India
ID NLM: 8708303
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
21
10
2020
accepted:
10
12
2020
pubmed:
27
1
2021
medline:
27
1
2021
entrez:
26
1
2021
Statut:
ppublish
Résumé
Currently, world is facing a global outbreak causing a pandemic threat known as COVID-19. This infectious disease is triggered by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Gut microbiota harbours multi species community with a strong impact on host immune homeostasis. However, our knowledge about this gut microbiota and its symbiotic relationship with immune activation in association with SARS-CoV-2 is limited. Unbalanced bacterial flora with too many opportunistic infections can shift immune system towards a cascade of inflammatory responses leading to multi organ damage. This review will highlight immune-regulation via various mechanisms in SARS-CoV-2 infection. Diet has an unbelievable influence on gut microbiome that allows a new state of homeostasis to be reached through timing, frequency and duration of intake. This review article focuses on gut, lung microbiota and immunomodulation with specific attention on immune activation by gut microbiota.
Identifiants
pubmed: 33495676
doi: 10.1007/s12291-020-00948-9
pii: 948
pmc: PMC7818076
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
266-277Informations de copyright
© Association of Clinical Biochemists of India 2021.
Déclaration de conflit d'intérêts
Conflicts of interestThe authors declare that they have no conflict of interest
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