Predictors for Rapid Progression of Coronary Calcification: An Optical Coherence Tomography Study.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
02 02 2021
Historique:
pubmed: 27 1 2021
medline: 14 10 2021
entrez: 26 1 2021
Statut: ppublish

Résumé

Background The role of coronary calcification in cardiovascular events and plaque stabilization is still being debated, and factors involved in the progression of coronary calcification are not fully understood. This study aimed to identify the predictors for rapid progression of coronary calcification. Methods and Results Patients with serial optical coherence tomography imaging at baseline and at 6 months were selected. Changes in the calcification index and predictors for progression of calcification were studied. Calcification index was defined as the product of the mean calcification arc and calcification length. Rapid progression of calcification was defined as an increase in the calcification index above the median value. Among 187 patients who had serial optical coherence tomography imaging, 235 calcified plaques were identified in 105 patients (56.1%) at baseline. After 6 months, the calcification index increased in 95.3% of calcified plaques from 132.0 to 178.2 (

Identifiants

pubmed: 33496191
doi: 10.1161/JAHA.120.019235
pmc: PMC7955445
doi:

Banques de données

ClinicalTrials.gov
['NCT01110538']

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e019235

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL142809
Pays : United States

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Auteurs

Akihiro Nakajima (A)

Cardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.

Makoto Araki (M)

Cardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.

Osamu Kurihara (O)

Cardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.

Yoshiyasu Minami (Y)

Department of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.

Tsunenari Soeda (T)

Department of Cardiovascular Medicine Nara Medical University Kashihara Nara Japan.

Taishi Yonetsu (T)

Department of Interventional Cardiology Tokyo Medical and Dental University Tokyo Japan.

Takumi Higuma (T)

Division of Cardiology Department of Internal Medicine St. Marianna University School of Medicine Kanagawa Japan.

Tsunekazu Kakuta (T)

Department of Cardiology Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.

Iris McNulty (I)

Cardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.

Hang Lee (H)

Biostatistics Center Massachusetts General HospitalHarvard Medical School Boston MA.

Rajeev Malhotra (R)

Cardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.

Sunao Nakamura (S)

Interventional Cardiology Unit New Tokyo Hospital Chiba Japan.

Ik-Kyung Jang (IK)

Cardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Division of Cardiology Kyung Hee University Hospital Seoul Korea.

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