Evaluation of the geroprotective effects of withaferin A in

Animals Drosophila Proteins / metabolism Drosophila melanogaster / drug effects Heat-Shock Proteins / metabolism Heat-Shock Response / drug effects Intestinal Mucosa / drug effects Longevity / drug effects Oxidative Stress / drug effects Permeability / drug effects Protective Agents / pharmacology Sex Factors Withanolides / pharmacology
Drosophila melanogaster lifespan stress response stress-resistance withaferin A

Journal

Aging
ISSN: 1945-4589
Titre abrégé: Aging (Albany NY)
Pays: United States
ID NLM: 101508617

Informations de publication

Date de publication:
26 01 2021
Historique:
received: 09 11 2020
accepted: 04 01 2021
pubmed: 27 1 2021
medline: 11 5 2021
entrez: 26 1 2021
Statut: ppublish

Résumé

Withanolides are a class of compounds usually found in plant extracts which are an attractive geroprotective drug design starting point. We evaluated the geroprotective properties of Withaferin A (WA)

Identifiants

DOI: 10.18632/aging.202572 PMID: 33498013 PMC: PMC7880378
pubmed: 33498013
pii: 202572
doi: 10.18632/aging.202572
pmc: PMC7880378
doi:

Substances chimiques

Drosophila Proteins 0
Heat-Shock Proteins 0
Protective Agents 0
Withanolides 0
withaferin A L6DO3QW4K5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1817-1841

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Auteurs

Liubov Koval (L)

Institute of Biology, Komi Science Centre, the Ural Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia.

Nadezhda Zemskaya (N)

Institute of Biology, Komi Science Centre, the Ural Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia.

Alexander Aliper (A)

Deep Longevity Ltd, Hong Kong Science and Technology Park, Hong Kong, China.

Alex Zhavoronkov (A)

Deep Longevity Ltd, Hong Kong Science and Technology Park, Hong Kong, China.

Alexey Moskalev (A)

Institute of Biology, Komi Science Centre, the Ural Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'arthropode › Protéines d'insecte › Protéines de Drosophila › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Chaperons moléculaires › Protéines du choc thermique › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Réaction de choc thermique › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Tissus › Membranes › Muqueuse › Muqueuse intestinale › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Phénomènes physiologiques › Longévité › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Phénomènes chimiques › Perméabilité › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Facteurs épidémiologiques › Facteurs sexuels › Evaluation of the geroprotective effects of...
questionsmedicales.fr › Facteurs biologiques › Composés phytochimiques › Phytostérols › Withanolides › Evaluation of the geroprotective effects of...