Toward stroke-free coronary surgery: The role of the anaortic off-pump bypass technique.


Journal

Journal of cardiac surgery
ISSN: 1540-8191
Titre abrégé: J Card Surg
Pays: United States
ID NLM: 8908809

Informations de publication

Date de publication:
Apr 2021
Historique:
revised: 06 01 2021
received: 14 11 2020
accepted: 13 01 2021
pubmed: 28 1 2021
medline: 15 5 2021
entrez: 27 1 2021
Statut: ppublish

Résumé

Surgical coronary revascularization remains the preferred strategy in a significant portion of patients with coronary artery disease due to superior long-term outcomes. However, there is a significant risk of perioperative neurologic injury that has influenced guideline recommendations. These complications occur in 1%-5% of patients, ranging from overt neurologic deficits with permanent disability, to subtle cerebral defects noted on neuroimaging that may result in slow cognitive and functional decline. The primary mechanism by which these events occur is thromboembolism from manipulation of the ascending aorta. This occurs during cardiopulmonary bypass, aortic cross-clamping, and partial occlusion clamping (side clamp). Elderly patients and patients with aortic atheroma are, therefore, at significantly increased risk. Initial surgical techniques addressed this by aggressively debriding or replacing the ascending aorta during coronary artery bypass grafting (CABG). Strategies then moved toward minimizing aortic manipulation through pump-assisted beating heart surgery and off-pump surgery with partial occlusion clamping or proximal anastomosis devices. Finally, anaortic off-pump CABG aims to avoid all manipulation of the ascending aorta through advanced off-pump grafting techniques combined with in situ and composite grafts. This has been demonstrated to result in the greatest reduction in risk. Establishing successful anaortic off-pump CABG programs requires subspecialization and focused interest groups dedicated to advancing CABG outcomes.

Identifiants

pubmed: 33502822
doi: 10.1111/jocs.15372
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1499-1510

Informations de copyright

© 2021 Wiley Periodicals LLC.

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Auteurs

Fabio Ramponi (F)

Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

Michael Seco (M)

Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

Russel John Legay Brereton (RJL)

Department of Cardiothoracic Surgery, Royal North Shore Hospital, Sydney, New South Wales, Australia.

Mario F L Gaudino (MFL)

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York, USA.

John D Puskas (JD)

Department of Cardiovascular Surgery, Mount Sinai Saint Luke's, New York, New York, USA.

Antonio M Calafiore (AM)

Department of Cardiovascular Diseases, Gemelli Molise, Campobasso, Italy.

Michael P Vallely (MP)

Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

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