Sexual and asexual development: two distinct programs producing the same tunicate.
tunicate, Botryllus schlosseri, embryogenesis, blastogenesis, development, stem cells, regeneration, organogenesis, transcription factors, evolution
Journal
Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691
Informations de publication
Date de publication:
26 01 2021
26 01 2021
Historique:
received:
02
11
2019
revised:
24
08
2020
accepted:
30
12
2020
entrez:
27
1
2021
pubmed:
28
1
2021
medline:
29
1
2022
Statut:
ppublish
Résumé
Colonial tunicates are the only chordate that possess two distinct developmental pathways to produce an adult body: either sexually through embryogenesis or asexually through a stem cell-mediated renewal termed blastogenesis. Using the colonial tunicate Botryllus schlosseri, we combine transcriptomics and microscopy to build an atlas of the molecular and morphological signatures at each developmental stage for both pathways. The general molecular profiles of these processes are largely distinct. However, the relative timing of organogenesis and ordering of tissue-specific gene expression are conserved. By comparing the developmental pathways of B. schlosseri with other chordates, we identify hundreds of putative transcription factors with conserved temporal expression. Our findings demonstrate that convergent morphology need not imply convergent molecular mechanisms but that it showcases the importance that tissue-specific stem cells and transcription factors play in producing the same mature body through different pathways.
Identifiants
pubmed: 33503429
pii: S2211-1247(20)31670-3
doi: 10.1016/j.celrep.2020.108681
pmc: PMC7949349
mid: NIHMS1667155
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
108681Subventions
Organisme : NIA NIH HHS
ID : R01 AG037968
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM100315
Pays : United States
Organisme : NIA NIH HHS
ID : R21 AG062948
Pays : United States
Organisme : NIAID NIH HHS
ID : R56 AI089968
Pays : United States
Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declarations of interests The authors declare no competing interests.
Références
Bioinformatics. 2015 Jan 15;31(2):166-9
pubmed: 25260700
Science. 2018 Jun 1;360(6392):
pubmed: 29700225
Cell. 1986 Jul 4;46(1):19-29
pubmed: 3013418
Bioinformatics. 2012 Oct 1;28(19):2520-2
pubmed: 22908215
Nat Ecol Evol. 2017 Nov;1(11):1722-1730
pubmed: 28963548
BMC Biol. 2015 Dec 23;13:113
pubmed: 26700477
Cell. 2018 Feb 8;172(4):650-665
pubmed: 29425488
Dev Dyn. 2007 Jul;236(7):1790-805
pubmed: 17557317
Science. 1988 Jul 1;241(4861):58-62
pubmed: 2898810
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
Nature. 2018 Dec;564(7736):425-429
pubmed: 30518860
Arch Ital Anat Embriol. 1955;60(1):33-67
pubmed: 14377796
Ciba Found Symp. 1994;182:92-110; discussion 110-20
pubmed: 7835159
Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15254-9
pubmed: 8986797
Cell Cycle. 2005 Dec;4(12):1736-40
pubmed: 16294024
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9148-53
pubmed: 10430910
Nature. 2019 May;569(7756):361-367
pubmed: 30959515
Dev Suppl. 1994;:135-42
pubmed: 7579514
J Exp Zool B Mol Dev Evol. 2021 Apr;336(3):250-266
pubmed: 32190983
J Exp Zool B Mol Dev Evol. 2011 Dec 15;316(8):562-73
pubmed: 21826788
Nat Commun. 2019 Aug 26;10(1):3857
pubmed: 31451684
Cell Stem Cell. 2008 Oct 9;3(4):456-64
pubmed: 18940736
Bioessays. 2009 Apr;31(4):478-86
pubmed: 19274660
Nature. 2019 Jun;570(7759):77-82
pubmed: 31086336
Nature. 2020 Sep;585(7825):357-362
pubmed: 32939066
Dev Biol. 1997 Jan 1;181(1):14-20
pubmed: 9015261
Zoolog Sci. 2014 Oct;31(10):645-52
pubmed: 25284383
PLoS One. 2014 May 01;9(5):e96434
pubmed: 24789338
Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):175-80
pubmed: 19098099
Dev Biol. 2019 Apr 15;448(2):293-308
pubmed: 30217596
Cell Tissue Res. 1993 Apr;272(1):115-27
pubmed: 8386984
OMICS. 2016 Mar;20(3):139-51
pubmed: 26983021
Science. 2015 Oct 16;350(6258):325-8
pubmed: 26472909
Dev Dyn. 2011 Feb;240(2):299-308
pubmed: 21246647
Dev Biol. 1983 Nov;100(1):64-119
pubmed: 6684600
Development. 2000 Feb;127(3):503-14
pubmed: 10631171
Development. 1990 Oct;110(2):521-8
pubmed: 2133553
Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8922-8
pubmed: 26195745
Dev Cell. 2013 Jan 14;24(1):76-88
pubmed: 23260626
Cell Tissue Res. 2008 Feb;331(2):555-64
pubmed: 17972103
Genome Biol. 2000;1(3):REVIEWS1017
pubmed: 11178242
Development. 2006 Jul;133(14):2683-93
pubmed: 16794033
Nat Commun. 2019 Jun 27;10(1):2812
pubmed: 31249294
Science. 2018 Jun 1;360(6392):981-987
pubmed: 29700229
Development. 2013 Jun;140(12):2463-7
pubmed: 23715539
Nat Commun. 2011;2:248
pubmed: 21427719
J Comp Neurol. 1999 Sep 27;412(3):527-41
pubmed: 10441238
Elife. 2013 Jul 02;2:e00569
pubmed: 23840927
Nature. 2019 Jul;571(7765):349-354
pubmed: 31292549
Bioinformatics. 2010 Jan 1;26(1):139-40
pubmed: 19910308
Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9585-90
pubmed: 10920202
Dev Dyn. 2005 Feb;232(2):468-78
pubmed: 15614778
Anat Rec. 1954 Feb;118(2):135-46
pubmed: 13138919
Nature. 2018 Dec;564(7734):64-70
pubmed: 30464347
Nat Methods. 2012 Mar 04;9(4):357-9
pubmed: 22388286
Dev Biol. 2009 Jul 15;331(2):113-28
pubmed: 19406116
Eur J Histochem. 2005 Jul-Sep;49(3):255-64
pubmed: 16216811
Int J Dev Biol. 2001;45(1):13-38
pubmed: 11291841
Nature. 2013 Nov 21;503(7476):360-4
pubmed: 24056933
Dev Dyn. 2008 May;237(5):1490-9
pubmed: 18386819
Curr Opin Genet Dev. 1999 Oct;9(5):542-7
pubmed: 10508695
Acta Morphol Neerl Scand. 1986;24(2):103-10
pubmed: 2882649
Cell. 1994 Jul 29;78(2):191-201
pubmed: 7913880
Bioinformatics. 2013 Jan 1;29(1):15-21
pubmed: 23104886
Development. 2009 Oct;136(20):3485-94
pubmed: 19783737
J Comp Neurol. 2002 Feb 4;443(2):124-35
pubmed: 11793351
J Comp Neurol. 2010 Feb 15;518(4):547-66
pubmed: 20020541
Nat Ecol Evol. 2020 Jun;4(6):820-830
pubmed: 32313176
J Exp Zool. 1999 Aug 15;285(2):158-69
pubmed: 10440727
Nature. 2018 Oct;562(7727):367-372
pubmed: 30283141
FASEB J. 2007 May;21(7):1335-44
pubmed: 17289924
Bioinformatics. 2009 Aug 15;25(16):2078-9
pubmed: 19505943
Genesis. 2015 Jan;53(1):34-47
pubmed: 25250532
Science. 2002 Mar 1;295(5560):1669-78
pubmed: 11872831
J Reprod Fertil. 1999 Jul;116(2):379-84
pubmed: 10615264
Science. 2013 Jul 26;341(6144):384-7
pubmed: 23888037
Sci Rep. 2014 Sep 24;4:6460
pubmed: 25248762
Cell. 2005 Dec 29;123(7):1351-60
pubmed: 16377573