PlexinA4-Semaphorin3A-mediated crosstalk between main cortical interneuron classes is required for superficial interneuron lamination.

Animals Cerebral Cortex / metabolism Interneurons / metabolism Mice Neocortex / metabolism Nerve Tissue Proteins / metabolism Receptors, Cell Surface / metabolism Semaphorin-3A / metabolism
PlexinA4 Semaphorin3A cortical interneurons guidepost neurons lamination

Journal

Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691

Informations de publication

Date de publication:
26 01 2021
Historique:
received: 07 07 2020
revised: 30 10 2020
accepted: 21 12 2020
entrez: 27 1 2021
pubmed: 28 1 2021
medline: 29 1 2022
Statut: ppublish

Résumé

In the mammalian cerebral cortex, the developmental events governing allocation of different classes of inhibitory interneurons (INs) to distinct cortical layers are poorly understood. Here we report that the guidance receptor PlexinA4 (PLXNA4) is upregulated in serotonin receptor 3a-expressing (HTR3A

Identifiants

DOI: 10.1016/j.celrep.2020.108644 PMID: 33503438
pubmed: 33503438
pii: S2211-1247(20)31633-8
doi: 10.1016/j.celrep.2020.108644
pii:
doi:

Substances chimiques

Nerve Tissue Proteins 0
Plxna4 protein, mouse 0
Receptors, Cell Surface 0
Semaphorin-3A 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

108644

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Greta Limoni (G)

Department of Basic Neuroscience, University of Geneva Medical School, 1211 Geneva, Switzerland; Department of Psychiatry, University of Geneva Medical School, 1211 Geneva, Switzerland.

Sahana Murthy (S)

Department of Basic Neuroscience, University of Geneva Medical School, 1211 Geneva, Switzerland; Department of Psychiatry, University of Geneva Medical School, 1211 Geneva, Switzerland.

Denis Jabaudon (D)

Department of Basic Neuroscience, University of Geneva Medical School, 1211 Geneva, Switzerland; Clinic of Neurology, Geneva University Hospital, 1211 Geneva, Switzerland. Electronic address: denis.jabaudon@unige.ch.

Alexandre Dayer (A)

Department of Basic Neuroscience, University of Geneva Medical School, 1211 Geneva, Switzerland; Department of Psychiatry, University of Geneva Medical School, 1211 Geneva, Switzerland.

Mathieu Niquille (M)

Department of Basic Neuroscience, University of Geneva Medical School, 1211 Geneva, Switzerland; Department of Psychiatry, University of Geneva Medical School, 1211 Geneva, Switzerland. Electronic address: mathieu.niquille@unige.ch.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Cellules › Neurones › Interneurones › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Néocortex › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › PlexinA4-Semaphorin3A-mediated crosstalk...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Sémaphorines › Sémaphorine-3A › PlexinA4-Semaphorin3A-mediated crosstalk...