Diagnostic pitfall of a rare variant of angiomyolipoma, epithelioid angiomyolipoma - a case report.
Epithelioid cells
PEComa
perivascular
renal cell carcinoma
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2020
2020
Historique:
received:
26
09
2020
accepted:
13
10
2020
entrez:
28
1
2021
pubmed:
29
1
2021
medline:
3
2
2021
Statut:
epublish
Résumé
Angiomyolipoma of the kidney is a common benign mesenchymal neoplasm of kidney. A rare variant, epithelioid angiomyolipoma, however, may show malignant behavior. We report a case of epithelioid angiomyolipoma in a patient not having tuberous sclerosis which was initially misdiagnosed as renal cell carcinoma. A 39-year-old woman presented with a history of flank pain. Ultrasonography revealed a left renal mass. Contrast-enhanced computed tomography (CECT) abdomen revealed mass involving hilum of the kidney. On core biopsy a possibility of renal cell carcinoma was suggested. The patient underwent radical nephrectomy. After immunohistochemical analysis, a final diagnosis of epithelioid angiomyolipoma was made. Renal epithelioid angiomyolipoma without adipocytic component is extremely rare. It is pivotal to keep a possibility of epithelioid angiomyolipoma whenever an epithelioid renal tumor is encountered showing marked pleomorphism and mitosis. The use of melanocytic markers and specific markers of renal cell carcinoma will aid the diagnosis.
Identifiants
pubmed: 33505578
doi: 10.11604/pamj.2020.37.210.26269
pii: PAMJ-37-210
pmc: PMC7813654
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
210Informations de copyright
Copyright: Michael Leonard Anthony et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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