Imaging technologies in the differential diagnosis and follow-up of brown tumor in primary hyperparathyroidism: Case report and review of the literature.

Brown tumor MRI Parathyroid adenoma Primary hyperparathyroidism

Journal

Bone reports
ISSN: 2352-1872
Titre abrégé: Bone Rep
Pays: United States
ID NLM: 101646176

Informations de publication

Date de publication:
Jun 2021
Historique:
received: 22 09 2020
revised: 05 12 2020
accepted: 28 12 2020
entrez: 28 1 2021
pubmed: 29 1 2021
medline: 29 1 2021
Statut: epublish

Résumé

Brown tumors are osteolytic lesions associated with hyperparathyroidism (HPT). They may involve various skeletal segments, but rarely the cranio-facial bones. We report a case of a young boy with a swelling of the jaw secondary to a brown tumor presenting as the first manifestation of primary HPT (PHPT). He was found to have brown tumor located in the skull, as well. Different imaging technologies were employed for the diagnosis and follow-up after parathyroidectomy. We enclose a review of the literature on the employment of such imaging technologies in the differential diagnosis of osteolytic lesions. A multidisciplinary approach comprising clinical, laboratory and imaging findings is essential for the differential diagnosis of brown tumor in PHPT.

Identifiants

pubmed: 33506077
doi: 10.1016/j.bonr.2020.100745
pii: S2352-1872(20)30505-2
pmc: PMC7815655
doi:

Types de publication

Case Reports

Langues

eng

Pagination

100745

Informations de copyright

© 2021 The Authors. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

S.M. served as speaker for Abiogen, Amgen, Bruno Farmaceutici, Diasorin, Eli Lilly, Shire, Sandoz, Takeda. He served in advisory board of Abiogen, Kyowa Kirin, Pfizer, UCB. All other authors declare no conflict of interests.

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Auteurs

Davide Diacinti (D)

Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Italy.
Department of Diagnostic and Molecular Imaging, Radiology and Radiotherapy, PTV Foundation "Tor Vergata" University, Rome, Italy.

Cristiana Cipriani (C)

Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.

Federica Biamonte (F)

Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Italy.
Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.

Jessica Pepe (J)

Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.

Luciano Colangelo (L)

Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Italy.
Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.

Endi Kripa (E)

Department of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.

Antonio Iannacone (A)

Department of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.

Martina Orlandi (M)

Department of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.

Vito Guarnieri (V)

Division of Medical Genetics, Fondazione IRCCS Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

Daniele Diacinti (D)

Department of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.

Salvatore Minisola (S)

Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.

Classifications MeSH