Transition of inflammatory bowel disease patients from pediatric to adult care: an observational study on a joint-visits approach.
Crohn’s disease
Pediatric IBD
SIBDQ
TRAQ
Transition
Ulcerative colitis
Journal
Italian journal of pediatrics
ISSN: 1824-7288
Titre abrégé: Ital J Pediatr
Pays: England
ID NLM: 101510759
Informations de publication
Date de publication:
28 Jan 2021
28 Jan 2021
Historique:
received:
24
10
2020
accepted:
21
01
2021
entrez:
29
1
2021
pubmed:
30
1
2021
medline:
25
2
2023
Statut:
epublish
Résumé
Transition from pediatric to adult care of patients affected by Inflammatory Bowel Disease (IBD) is a critical step that needs specific care and multidisciplinary involvement. The aim of our study was to evaluate the outcome of the transition process of a cohort of IBD patients, exploring their readiness and the possible impact on quality of life. This observational study followed transitioned IBD patients from pediatric to adult care. Transition was carried-out through combined visits, jointly performed by the pediatrician and the adult gastroenterologist. Clinical data were collected before and after transition. A subgroup of patients was submitted to an anonymous online questionnaire of 38 items based on the validated questionnaires TRAQ and SIBDQ within the first 6 months from the beginning of the transition process. Eighty-two patients with IBD were enrolled, with a mean age at transition of 20.2±2.7 years. Before transition, 40.2% of patients already had major surgery and 64.6% started biologics. At transition, 24% of patients were in moderate to severe active phase of their disease and 40% of them had already been treated with ≥ 2 biologics. The mean score of the TRAQ questionnaires collected is 3.4±1.5 and the mean score of SIBDQ is 53.9±9.8. A significant association was found between a TRAQ mean score > 3 and a SIBDQ > 50 (p=0.0129). Overall, 75% of patients had a positive opinion of the transition model adopted. A strong association has been found between TRAQ and SIBDQ questionnaires, showing how transition readiness has a direct impact on the quality of life of the young adult with IBD.
Sections du résumé
BACKGROUND
BACKGROUND
Transition from pediatric to adult care of patients affected by Inflammatory Bowel Disease (IBD) is a critical step that needs specific care and multidisciplinary involvement. The aim of our study was to evaluate the outcome of the transition process of a cohort of IBD patients, exploring their readiness and the possible impact on quality of life.
METHODS
METHODS
This observational study followed transitioned IBD patients from pediatric to adult care. Transition was carried-out through combined visits, jointly performed by the pediatrician and the adult gastroenterologist. Clinical data were collected before and after transition. A subgroup of patients was submitted to an anonymous online questionnaire of 38 items based on the validated questionnaires TRAQ and SIBDQ within the first 6 months from the beginning of the transition process.
RESULTS
RESULTS
Eighty-two patients with IBD were enrolled, with a mean age at transition of 20.2±2.7 years. Before transition, 40.2% of patients already had major surgery and 64.6% started biologics. At transition, 24% of patients were in moderate to severe active phase of their disease and 40% of them had already been treated with ≥ 2 biologics. The mean score of the TRAQ questionnaires collected is 3.4±1.5 and the mean score of SIBDQ is 53.9±9.8. A significant association was found between a TRAQ mean score > 3 and a SIBDQ > 50 (p=0.0129). Overall, 75% of patients had a positive opinion of the transition model adopted.
CONCLUSIONS
CONCLUSIONS
A strong association has been found between TRAQ and SIBDQ questionnaires, showing how transition readiness has a direct impact on the quality of life of the young adult with IBD.
Identifiants
pubmed: 33509223
doi: 10.1186/s13052-021-00977-x
pii: 10.1186/s13052-021-00977-x
pmc: PMC7844940
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
18Références
J Pediatr Gastroenterol Nutr. 2013 Apr;56(4):449-58
pubmed: 23287808
Gut. 2017 Jun;66(6):988-1000
pubmed: 28228488
Dig Dis Sci. 2013 Feb;58(2):519-25
pubmed: 22926499
Clin Gastroenterol Hepatol. 2010 Apr;8(4):357-63
pubmed: 20096379
J Crohns Colitis. 2011 Dec;5(6):509-19
pubmed: 22115368
Acta Paediatr. 2019 Feb;108(2):333-338
pubmed: 29926962
Gastroenterol Clin Biol. 2008 May;32(5 Pt 1):451-9
pubmed: 18472377
Inflamm Bowel Dis. 2019 Jan 1;25(1):45-55
pubmed: 29893932
World J Gastroenterol. 2017 May 14;23(18):3349-3355
pubmed: 28566896
Inflamm Bowel Dis. 2021 Jan 1;27(1):49-57
pubmed: 32109284
Acad Pediatr. 2014 Jul-Aug;14(4):415-22
pubmed: 24976354
Gut. 2006 Jun;55(6):749-53
pubmed: 16698746
Inflamm Bowel Dis. 2006 Mar;12(3):199-204
pubmed: 16534421
Inflamm Bowel Dis. 2016 Mar;22(3):702-8
pubmed: 26841222
Dig Liver Dis. 2019 Apr;51(4):524-528
pubmed: 30704905
Am J Gastroenterol. 1996 Aug;91(8):1571-8
pubmed: 8759664
Aliment Pharmacol Ther. 2019 Feb;49(4):419-428
pubmed: 30637837
Inflamm Bowel Dis. 2008 Dec;14(12):1660-6
pubmed: 18623174