Silk derived formulations for accelerated wound healing in diabetic mice.

Aloe vera Diabetes Fibroin Sericin Silk Skin wound

Journal

PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425

Informations de publication

Date de publication:
2021
Historique:
received: 23 04 2020
accepted: 02 10 2020
entrez: 29 1 2021
pubmed: 30 1 2021
medline: 30 1 2021
Statut: epublish

Résumé

The present study aimed to prepare effective silk derived formulations in combination with plant extract ( Diabetes was induced in albino mice by using alloxan monohydrate. After successful induction of diabetes in mice, excision wounds were created via biopsy puncture (6 mm). Wound healing effect of silk sericin (5%) and silk fibroin (5%) individually and in combination with 5% The results indicated that the best biocompatible silk combination was of 5% silk fibroin and 5% It can be concluded that a combination of

Sections du résumé

BACKGROUND BACKGROUND
The present study aimed to prepare effective silk derived formulations in combination with plant extract (
METHODS METHODS
Diabetes was induced in albino mice by using alloxan monohydrate. After successful induction of diabetes in mice, excision wounds were created via biopsy puncture (6 mm). Wound healing effect of silk sericin (5%) and silk fibroin (5%) individually and in combination with 5%
RESULTS RESULTS
The results indicated that the best biocompatible silk combination was of 5% silk fibroin and 5%
CONCLUSION CONCLUSIONS
It can be concluded that a combination of

Identifiants

pubmed: 33510964
doi: 10.7717/peerj.10232
pii: 10232
pmc: PMC7798629
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e10232

Informations de copyright

© 2021 Tariq et al.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

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Auteurs

Muniba Tariq (M)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Hafiz Muhammad Tahir (HM)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Samima Asad Butt (SA)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Shaukat Ali (S)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Asma Bashir Ahmad (AB)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Chand Raza (C)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Muhammad Summer (M)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Ali Hassan (A)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Junaid Nadeem (J)

Department of Zoology, Government College University Lahore, Lahore, Pakistan.

Classifications MeSH