Joint hypothesis testing of the area under the receiver operating characteristic curve and the Youden index.
AUC
IUT
Youden index
joint confidence region
order restrictive inference
Journal
Pharmaceutical statistics
ISSN: 1539-1612
Titre abrégé: Pharm Stat
Pays: England
ID NLM: 101201192
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
revised:
21
11
2020
received:
29
07
2020
accepted:
14
01
2021
pubmed:
30
1
2021
medline:
26
11
2021
entrez:
29
1
2021
Statut:
ppublish
Résumé
In the receiver operating characteristic (ROC) analysis, the area under the ROC curve (AUC) serves as an overall measure of diagnostic accuracy. Another popular ROC index is the Youden index (J), which corresponds to the maximum sum of sensitivity and specificity minus one. Since the AUC and J describe different aspects of diagnostic performance, we propose to test if a biomarker beats the pre-specified targeting values of AUC
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
657-674Informations de copyright
© 2021 John Wiley & Sons Ltd.
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