Ocular fundus abnormalities in cats affected by systemic hypertension: Prevalence, characterization, and outcome of treatment.
amlodipine
cat
eye
ocular fundus abnormalities
systemic hypertension
Journal
Veterinary ophthalmology
ISSN: 1463-5224
Titre abrégé: Vet Ophthalmol
Pays: England
ID NLM: 100887377
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
revised:
23
12
2020
received:
21
05
2020
accepted:
31
12
2020
pubmed:
30
1
2021
medline:
15
9
2021
entrez:
29
1
2021
Statut:
ppublish
Résumé
To determine the prevalence of ocular fundus abnormalities in cats with a diagnosis of systemic hypertension, to characterize the abnormalities observed, and to evaluate ophthalmoscopic evolution during treatment with amlodipine besylate. Cats diagnosed as affected by SHP in a 2-year period. Systemic hypertension was assessed by oscillometric blood pressure measurement, and its etiology was also established. All the cats received an ophthalmic examination, and ocular lesions were classified with a score from 0 (no abnormalities) to 4 (severe abnormalities). All cats received amlodipine besylate by mouth, and those that showed fundus abnormalities were regularly rechecked from 7 to 365 days after diagnosis. Data were statistically analyzed to compare P A total of 225 cats were enrolled in the study, and the prevalence of fundus abnormalities was 58.6% (21.2%: grade 1; 18.2%: grade 2; 36.4%: grade 3; and 24.2%: grade 4). Systemic hypertension was diagnosed concurrently with chronic renal failure (60.4%), hyperthyroidism (28.9%), both chronic renal failure and hyperthyroidism (7.6%), and hypertrophic myocardiopathy (3.1%). A significant effect of P This study showed that fundus abnormalities are common in hypertensive cats at the time of the systemic diagnosis, and most of the abnormalities are moderate to severe. Treatment with amlodipine appeared to improve ophthalmic lesions over time.
Substances chimiques
Antihypertensive Agents
0
Amlodipine
1J444QC288
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
185-194Informations de copyright
© 2021 American College of Veterinary Ophthalmologists.
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