Impact of the lockdown on the burden of COVID-19 in outpatient care in France, spring 2020.


Journal

Infectious diseases (London, England)
ISSN: 2374-4243
Titre abrégé: Infect Dis (Lond)
Pays: England
ID NLM: 101650235

Informations de publication

Date de publication:
05 2021
Historique:
pubmed: 30 1 2021
medline: 13 4 2021
entrez: 29 1 2021
Statut: ppublish

Résumé

To limit the spread of SARS-CoV-2 several countries implemented measures to reduce the number of contacts such as a national lockdown. We estimated the impact of the first lockdown on the burden of COVID-19 in the community in France. Physicians participating in the French Sentinelles network reported the number of patients with an acute respiratory infection (ARI) seen in consultation and performed nasopharyngeal swabs in a sample of these patients (first patient of the week). The swabs were tested by RT-PCR for the presence of SARS-CoV-2. Clinical and virological data were combined to estimate ARI incidence attributable to SARS-CoV-2 from 17 March to 10 May 2020. The incidence of ARI attributable to COVID-19 decreased after the second week of the lockdown period from 142 (95%CI [101; 183]) to 41 (95%CI [21; 60]) per 100,000 population. A decrease was observed in all areas in metropolitan France. The youngest age groups (<15-years-old) were least affected with a cumulated incidence estimated to 14 per 100,000 population during the study period. The data collected in primary care suggests that the first lockdown implemented in France during spring 2020 significantly reduced the incidence of acute respiratory infections including COVID-19 in France and limited the geographic spread of SARS-CoV-2.

Sections du résumé

BACKGROUND
To limit the spread of SARS-CoV-2 several countries implemented measures to reduce the number of contacts such as a national lockdown. We estimated the impact of the first lockdown on the burden of COVID-19 in the community in France.
METHODS
Physicians participating in the French Sentinelles network reported the number of patients with an acute respiratory infection (ARI) seen in consultation and performed nasopharyngeal swabs in a sample of these patients (first patient of the week). The swabs were tested by RT-PCR for the presence of SARS-CoV-2. Clinical and virological data were combined to estimate ARI incidence attributable to SARS-CoV-2 from 17 March to 10 May 2020.
RESULTS
The incidence of ARI attributable to COVID-19 decreased after the second week of the lockdown period from 142 (95%CI [101; 183]) to 41 (95%CI [21; 60]) per 100,000 population. A decrease was observed in all areas in metropolitan France. The youngest age groups (<15-years-old) were least affected with a cumulated incidence estimated to 14 per 100,000 population during the study period.
CONCLUSIONS
The data collected in primary care suggests that the first lockdown implemented in France during spring 2020 significantly reduced the incidence of acute respiratory infections including COVID-19 in France and limited the geographic spread of SARS-CoV-2.

Identifiants

pubmed: 33512254
doi: 10.1080/23744235.2021.1880024
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

376-381

Auteurs

Cécile Souty (C)

Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé publique (IPLESP), Paris, France.

Caroline Guerrisi (C)

Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé publique (IPLESP), Paris, France.

Shirley Masse (S)

UR 7310, Laboratoire de Virologie, Université de Corse, Corte, France.

Bruno Lina (B)

Laboratoire de Virologie des HCL, Institut des Agents Infectieux, CNR des virus à transmission respiratoire (dont la grippe), Hôpital de la Croix Rousse, Lyon, France.

Sylvie van der Werf (S)

National Reference Center for Respiratory Viruses, Molecular Genetics of RNA Viruses, CNRS UMR 3569, Institut Pasteur, Université de Paris, Paris, France.

Sibylle Bernard-Stoecklin (S)

Santé Publique France, Direction des maladies infectieuses, Saint-Maurice, France.

Clément Turbelin (C)

Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé publique (IPLESP), Paris, France.

Alessandra Falchi (A)

UR 7310, Laboratoire de Virologie, Université de Corse, Corte, France.

Thomas Hanslik (T)

Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé publique (IPLESP), Paris, France.
Faculty of Health Sciences Simone Veil, University of Versailles Saint Quentin - University of Paris, Versailles, France.
Assistance Publique-Hôpitaux de Paris (APHP), Hôpital Ambroise Paré, Service de Médecine Interne, Boulogne-Billancourt, France.

Thierry Blanchon (T)

Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé publique (IPLESP), Paris, France.

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