ENDO-ERN expert opinion on the differential diagnosis of pubertal delay.
Constitutional delay of growth and puberty
Gonadal dysgenesis
Hypogonadism
Primary ovarian insufficiency
Pubertal delay
Sex steroid priming
Journal
Endocrine
ISSN: 1559-0100
Titre abrégé: Endocrine
Pays: United States
ID NLM: 9434444
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
30
10
2020
accepted:
09
01
2021
pubmed:
30
1
2021
medline:
9
7
2021
entrez:
29
1
2021
Statut:
ppublish
Résumé
The differential diagnoses of pubertal delay include hypergonadotropic hypogonadism and congenital hypogonadotropic hypogonadism (CHH), as well as constitutional delay of growth and puberty (CDGP). Distinguishing between CDGP and CHH may be challenging, and the scientific community has been struggling to develop diagnostic tests that allow an accurate differential diagnosis. Indeed, an adequate and timely management is critical in order to enable optimal clinical and psychosocial outcomes of the different forms of pubertal delays. In this review, we provide an updated insight on the differential diagnoses of pubertal delay, including the available tests, their meanings and accuracy, as well as some clues to effectively orientate towards either constitutional pubertal delay or pathologic CHH and hypergonadotropic hypogonadism.
Identifiants
pubmed: 33512657
doi: 10.1007/s12020-021-02626-z
pii: 10.1007/s12020-021-02626-z
pmc: PMC8016789
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
681-688Références
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