Targeting Chloride Ion Channels: New Insights into the Mechanism of Action of the Marine Toxin Azaspiracid.

Adenosine Triphosphate / metabolism Chloride Channels / metabolism Dose-Response Relationship, Drug HEK293 Cells Humans Marine Toxins / chemistry Spiro Compounds / chemistry

Journal

Chemical research in toxicology
ISSN: 1520-5010
Titre abrégé: Chem Res Toxicol
Pays: United States
ID NLM: 8807448

Informations de publication

Date de publication:
15 03 2021
Historique:
pubmed: 30 1 2021
medline: 25 9 2021
entrez: 29 1 2021
Statut: ppublish

Résumé

Azaspiracids (AZAs) are marine toxins produced by dinoflagellates belonging to the genera

Identifiants

DOI: 10.1021/acs.chemrestox.0c00494 PMID: 33512997
pubmed: 33512997
doi: 10.1021/acs.chemrestox.0c00494
doi:

Substances chimiques

Chloride Channels 0
Marine Toxins 0
Spiro Compounds 0
azaspiracid 0
Adenosine Triphosphate 8L70Q75FXE

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

865-879

Auteurs

Andrea Boente-Juncal (A)

Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus Universitario s/n, 27002 Lugo, España.

Sandra Raposo-García (S)

Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus Universitario s/n, 27002 Lugo, España.

M Carmen Louzao (MC)

Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus Universitario s/n, 27002 Lugo, España.
ORCID: 0000-0002-3072-0637

Carmen Vale (C)

Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus Universitario s/n, 27002 Lugo, España.
ORCID: 0000-0002-9842-6223

Luis M Botana (LM)

Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus Universitario s/n, 27002 Lugo, España.

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › Adénosine triphosphate › Targeting Chloride Ion Channels: New Insights...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux chlorure › Targeting Chloride Ion Channels: New Insights...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Targeting Chloride Ion Channels: New Insights...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Targeting Chloride Ion Channels: New Insights...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Targeting Chloride Ion Channels: New Insights...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Toxines de la flore et de la faune marines › Targeting Chloride Ion Channels: New Insights...
questionsmedicales.fr › Composés polycycliques › Spiranes › Targeting Chloride Ion Channels: New Insights...