The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction.
DNA damage response
TP53 mutational status
cancer progression
cancer risk
cancer therapy
interactions
telomere homeostasis
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
27 Jan 2021
27 Jan 2021
Historique:
received:
06
12
2020
revised:
18
01
2021
accepted:
23
01
2021
entrez:
30
1
2021
pubmed:
31
1
2021
medline:
31
1
2021
Statut:
epublish
Résumé
The disruption of genomic integrity due to the accumulation of various kinds of DNA damage, deficient DNA repair capacity, and telomere shortening constitute the hallmarks of malignant diseases. DNA damage response (DDR) is a signaling network to process DNA damage with importance for both cancer development and chemotherapy outcome. DDR represents the complex events that detect DNA lesions and activate signaling networks (cell cycle checkpoint induction, DNA repair, and induction of cell death).
Identifiants
pubmed: 33513745
pii: cancers13030479
doi: 10.3390/cancers13030479
pmc: PMC7865496
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Grantová Agentura České Republiky
ID : 18-09709S
Organisme : Grantová Agentura České Republiky
ID : 19-10543S
Organisme : Agentura Pro Zdravotnický Výzkum České Republiky
ID : NV18-00199
Organisme : Grantová Agentura, Univerzita Karlova
ID : PROGRES Q 28
Organisme : Grantová Agentura, Univerzita Karlova
ID : UNCE/MED/006
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : CZ.02.1.01/0.0./0.0/16_019/0000787
Références
Cell Growth Differ. 1999 Oct;10(10):665-75
pubmed: 10547070
Epigenomics. 2014 Apr;6(2):179-91
pubmed: 24811787
Cold Spring Harb Perspect Biol. 2011 Jan 01;3(1):a000745
pubmed: 20980439
Mutat Res. 2019 Apr - Jun;780:15-28
pubmed: 31395346
Oncotarget. 2017 Jan 3;8(1):624-643
pubmed: 27880943
J Mol Biol. 2004 Feb 20;336(3):639-54
pubmed: 15095978
Mol Aspects Med. 2019 Oct;69:2-9
pubmed: 31233770
Cell Death Differ. 2012 Sep;19(9):1525-35
pubmed: 22421968
Protein Cell. 2019 Nov;10(11):808-824
pubmed: 31115790
Cell Rep. 2019 Jul 30;28(5):1370-1384.e5
pubmed: 31365877
Cell Death Differ. 2018 Jan;25(1):93-103
pubmed: 29099489
Clin Cancer Res. 2012 Nov 1;18(21):5878-87
pubmed: 22966016
Nat Commun. 2016 Dec 13;7:13837
pubmed: 27958275
World J Gastroenterol. 2015 Jan 7;21(1):84-93
pubmed: 25574081
Cancer Lett. 2013 May 28;332(2):237-48
pubmed: 22261329
Biomolecules. 2020 Feb 14;10(2):
pubmed: 32075132
Cancers (Basel). 2018 May 06;10(5):
pubmed: 29734785
Mol Cancer Res. 2010 May;8(5):701-16
pubmed: 20407015
Clin Cancer Res. 2020 Sep 15;26(18):4767-4776
pubmed: 32611648
Nat Genet. 1995 Jun;10(2):188-95
pubmed: 7663514
Cell. 2011 Mar 4;144(5):646-74
pubmed: 21376230
PLoS One. 2017 Aug 10;12(8):e0180489
pubmed: 28797035
BMC Cancer. 2020 Nov 2;20(1):1053
pubmed: 33138793
Carcinogenesis. 2004 Jan;25(1):11-9
pubmed: 14555612
Mutat Res Genet Toxicol Environ Mutagen. 2018 Dec;836(Pt A):13-21
pubmed: 30389156
J Gastrointest Cancer. 2016 Dec;47(4):409-416
pubmed: 27342962
Mutagenesis. 2020 Jul 11;35(3):261-271
pubmed: 32083302
Cell Mol Biol (Noisy-le-grand). 2020 Jun 25;66(4):110-119
pubmed: 32583791
Pharmacol Ther. 2015 May;149:124-38
pubmed: 25512053
FEBS Lett. 1999 May 7;450(3):197-204
pubmed: 10359074
Cell. 2012 Jun 22;149(7):1536-48
pubmed: 22726440
Trends Genet. 2012 Mar;28(3):128-36
pubmed: 22265392
J Zhejiang Univ Sci B. 2019 Jun;20(6):457-466
pubmed: 31090271
Adv Protein Chem Struct Biol. 2019;115:297-324
pubmed: 30798935
Oncotarget. 2018 Jan 23;9(42):26616-26624
pubmed: 29928473
Cell. 2017 Feb 9;168(4):644-656
pubmed: 28187286
Cold Spring Harb Symp Quant Biol. 2000;65:127-33
pubmed: 12760027
Cold Spring Harb Perspect Med. 2016 Nov 1;6(11):
pubmed: 27503997
Clin Cancer Res. 2019 May 15;25(10):3084-3095
pubmed: 30792217
Cancers (Basel). 2011 Mar 03;3(1):994-1013
pubmed: 24212651
J Clin Oncol. 2005 Oct 20;23(30):7518-28
pubmed: 16172461
Oncotarget. 2016 Apr 26;7(17):23156-69
pubmed: 26735576
Nature. 2019 Feb;566(7743):249-253
pubmed: 30700914
Br J Cancer. 2019 Apr;120(8):797-805
pubmed: 30894685
Pediatr Int. 2019 Aug;61(8):759-767
pubmed: 31211452
EMBO J. 2001 Feb 15;20(4):914-23
pubmed: 11179235
Cold Spring Harb Perspect Med. 2017 May 1;7(5):
pubmed: 28289249
Oncogene. 2002 Jan 24;21(5):731-7
pubmed: 11850801
Cancer Res. 2001 Jan 1;61(1):88-96
pubmed: 11196204
Carcinogenesis. 2012 Jul;33(7):1346-51
pubmed: 22581836
Mutat Res. 2020 Oct - Dec;858-860:503253
pubmed: 33198934
Cell. 1990 Jun 1;61(5):759-67
pubmed: 2188735
Mutagenesis. 2012 Mar;27(2):211-8
pubmed: 22294769
J Biomed Biotechnol. 2012;2012:170325
pubmed: 22911014
Int J Mol Sci. 2019 Dec 08;20(24):
pubmed: 31817996
Gastroenterology. 2015 Oct;149(5):1177-1190.e3
pubmed: 26216840
Int J Radiat Biol. 2005 Jun;81(6):445-58
pubmed: 16308915
Oncol Rep. 2013 Oct;30(4):1581-6
pubmed: 23846616
Gut. 2002 Jun;50(6):834-9
pubmed: 12010886
J Clin Oncol. 2016 Dec 20;34(36):4354-4361
pubmed: 27998224
Mutagenesis. 2017 Oct 17;32(5):533-542
pubmed: 29048575
Cancer Metastasis Rev. 2018 Mar;37(1):173-187
pubmed: 29322354
J Drugs Dermatol. 2013 Mar;12(3):336-40
pubmed: 23545918
J Mol Cell Biol. 2019 Jul 19;11(7):605-609
pubmed: 31283823
Biochem Biophys Res Commun. 2005 Jun 10;331(3):881-90
pubmed: 15865944
J Cancer Res Clin Oncol. 2020 Nov;146(11):2851-2859
pubmed: 32743759
Cell Metab. 2015 Jan 6;21(1):81-94
pubmed: 25565207
J Clin Oncol. 2005 Aug 20;23(24):5635-43
pubmed: 16110022
Nucleic Acids Res. 2008 Mar;36(5):1555-66
pubmed: 18208837
Subcell Biochem. 2014;85:321-36
pubmed: 25201202
Clin Cancer Res. 2015 Nov 1;21(21):4780-5
pubmed: 26362996
Mutagenesis. 2002 Mar;17(2):149-56
pubmed: 11880544
Hum Mutat. 2016 Sep;37(9):865-76
pubmed: 27328919
Carcinogenesis. 2005 May;26(5):867-74
pubmed: 15471900
Int J Mol Sci. 2020 Oct 27;21(21):
pubmed: 33120969
J Biol Chem. 2008 Mar 7;283(10):6572-83
pubmed: 18162465
Cancers (Basel). 2019 Dec 09;11(12):
pubmed: 31835405
Int J Radiat Biol. 2019 Jun;95(6):667-679
pubmed: 30753097
Dig Dis Sci. 2015 Mar;60(3):762-72
pubmed: 25492499
Acta Oncol. 2006;45(1):61-6
pubmed: 16464797
Cancers (Basel). 2020 Jun 28;12(7):
pubmed: 32605254
Int J Mol Sci. 2020 Aug 03;21(15):
pubmed: 32756484
Curr Probl Cancer. 2017 Jul - Aug;41(4):302-315
pubmed: 28662958
Cell. 1993 Nov 19;75(4):817-25
pubmed: 8242752
Pharmacol Ther. 2019 Nov;203:107391
pubmed: 31299316
Nat Cell Biol. 2007 May;9(5):573-80
pubmed: 17417627
J Biol Chem. 2001 Oct 19;276(42):39359-67
pubmed: 11483599
J Clin Invest. 2018 Apr 2;128(4):1371-1383
pubmed: 29480819
DNA Repair (Amst). 2014 Jul;19:199-213
pubmed: 24780560
Int J Mol Sci. 2019 Nov 28;20(23):
pubmed: 31795192
Cell Death Differ. 2018 Jan;25(1):114-132
pubmed: 29125603
Clin Cancer Res. 2017 Aug 1;23(15):4086-4094
pubmed: 28223274
J Mol Cell Biol. 2020 Sep 1;12(9):674-687
pubmed: 32722796
Cancer Biomark. 2020 Sep 18;:
pubmed: 32986661
J Theor Biol. 2019 Jan 7;460:144-152
pubmed: 30315815
Ann Surg Oncol. 2013 Dec;20 Suppl 3:S583-9
pubmed: 23744553
Cell Death Differ. 2019 Jan;26(2):199-212
pubmed: 30538286
Annu Rev Med. 2015;66:129-43
pubmed: 25423595
Cell Death Differ. 2018 Jan;25(1):104-113
pubmed: 29149101
Nature. 2007 Jun 28;447(7148):1130-4
pubmed: 17554337
EMBO J. 2017 Aug 1;36(15):2280-2295
pubmed: 28607003
Gastroenterology Res. 2018 Aug;11(4):264-273
pubmed: 30116425
Nature. 2015 Apr 2;520(7545):57-62
pubmed: 25799988
Mitochondrion. 2019 Jul;47:54-63
pubmed: 31071450
Clin Cancer Res. 2013 Nov 1;19(21):6044-56
pubmed: 24036853
Gynecol Oncol. 2021 Jan;160(1):322-332
pubmed: 33160694
Science. 2004 Feb 13;303(5660):1010-4
pubmed: 14963330
Cold Spring Harb Perspect Med. 2016 May 02;6(5):
pubmed: 27048304
Cell. 2006 Jul 14;126(1):121-34
pubmed: 16839881
Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11037-42
pubmed: 9380755
Nature. 2013 Feb 28;494(7438):492-496
pubmed: 23446422
Nat Commun. 2020 Aug 17;11(1):4124
pubmed: 32807787
Radiother Oncol. 2018 Mar;126(3):450-464
pubmed: 29054375
Mol Cancer Ther. 2016 Apr;15(4):593-607
pubmed: 26826118
Cancer Res. 1990 Dec 1;50(23):7717-22
pubmed: 2253215
DNA Repair (Amst). 2016 Feb;38:94-101
pubmed: 26704428
J Clin Oncol. 2014 Jun 20;32(18):1895-901
pubmed: 24821881
Appl Biochem Biotechnol. 2018 Nov;186(3):764-778
pubmed: 29730783
Ann Oncol. 2006 May;17(5):842-7
pubmed: 16524972
Int J Mol Sci. 2020 Apr 02;21(7):
pubmed: 32252452
Carcinogenesis. 2007 Jun;28(6):1241-6
pubmed: 17259658
Mutat Res. 2019 Sep;845:403065
pubmed: 31561886
Oncotarget. 2018 Apr 17;9(29):20508-20523
pubmed: 29755668
Mutat Res. 2019 Jul;843:95-110
pubmed: 31421745
Cancers (Basel). 2020 Jun 25;12(6):
pubmed: 32630478
J Mol Cell Biol. 2019 Apr 1;11(4):267-276
pubmed: 30496442
Biomolecules. 2020 Mar 08;10(3):
pubmed: 32182711