Contact, high-resolution spatial diffuse reflectance imaging system for skin condition diagnosis: a first-in-human clinical trial.
contact imaging
diffuse reflectance
multipixel sensor
optical properties
skin characterization
tissue oxygen saturation
wearable device
Journal
Journal of biomedical optics
ISSN: 1560-2281
Titre abrégé: J Biomed Opt
Pays: United States
ID NLM: 9605853
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
01
09
2020
accepted:
15
12
2020
entrez:
30
1
2021
pubmed:
31
1
2021
medline:
25
9
2021
Statut:
ppublish
Résumé
Oxygenation is one of the skin tissue physiological properties to follow for patient care management. Furthermore, long-term monitoring of such parameters is needed at the patient bed as well as outside the hospital. Diffuse reflectance spectroscopy has been widely used for this purpose. The aim of the study is to propose a low-cost system for the long-term measurement of skin physiological parameters in contact. We have developed a low-cost, wearable, CMOS-based device. We propose an original method for processing diffuse reflectance data to calculate the tissue oxygen saturation (StO2). We tested the device for the assessment of tissue oxygenation during a first-in-human clinical trial that took place at the Grenoble University Hospital France. The results of this clinical trial show a good accordance between our sensor and commercial devices used a reference.
Identifiants
pubmed: 33515218
pii: JBO-200286R
doi: 10.1117/1.JBO.26.1.012706
pmc: PMC7846121
doi:
Types de publication
Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Phys Med Biol. 2013 Jun 7;58(11):R37-61
pubmed: 23666068
Med Biol Eng Comput. 2020 Feb;58(2):239-247
pubmed: 31741291
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:4640-4643
pubmed: 33019028
Comput Methods Programs Biomed. 2003 Feb;70(2):179-86
pubmed: 12507793
Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:3352-3355
pubmed: 31946599
J Biomed Opt. 2013 Sep;18(9):095002
pubmed: 24064948
Clin Plast Surg. 1992 Oct;19(4):783-97
pubmed: 1339636
J Biomed Opt. 2018 Nov;23(11):1-9
pubmed: 30426730
J Biomed Opt. 2014;19(11):115002
pubmed: 25387084
J Biomed Opt. 2010 Mar-Apr;15(2):025001
pubmed: 20459242
Opt Express. 2009 Dec 21;17(26):23396-409
pubmed: 20052047
Med Phys. 1992 Jul-Aug;19(4):879-88
pubmed: 1518476
J Opt Soc Am A Opt Image Sci Vis. 2007 Apr;24(4):1011-25
pubmed: 17361287
J Biomed Opt. 2016 Jun 1;21(6):65003
pubmed: 27281063
Sleep. 2016 Jun 01;39(6):1197-9
pubmed: 26951398
J Biomed Opt. 2008 Sep-Oct;13(5):050501
pubmed: 19021373
J Biophotonics. 2015 Apr;8(4):309-16
pubmed: 25491716
Plast Reconstr Surg. 2010 Jan;125(1):177-185
pubmed: 20048610