Effect of early kangaroo mother care on time to full feeds in preterm infants - A prospective cohort study.
Early KMC
Neonate
Skin to skin contact
Time to full feeds
mother's own milk
Journal
Early human development
ISSN: 1872-6232
Titre abrégé: Early Hum Dev
Pays: Ireland
ID NLM: 7708381
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
06
10
2020
revised:
07
01
2021
accepted:
12
01
2021
pubmed:
1
2
2021
medline:
15
12
2021
entrez:
31
1
2021
Statut:
ppublish
Résumé
Kangaroo mother care (KMC) is known to reduce neonatal mortality and morbidity. In preterm neonates, KMC is usually initiated only after stabilization. We aimed to assess if early initiation of KMC starting within the first week of life is safe, and reduces the time to full feeds (TFF) in preterm neonates. Prospective cohort study. Preterm neonates (Gestation ≤ 34 weeks, Birth weight ≤ 1250 g). This was studied in two epochs, (epoch 1) which was before early KMC vs. epoch 2 which was after implementation of early KMC even if they needed respiratory support, with umbilical/central lines in situ. The primary outcome of the study was time to establish full feeds (TFF) of 150 ml/kg/day. The neonatal demographic characteristics were comparable between epoch 1 and epoch 2 except for lower gestational age, higher surfactant, and any respiratory support in epoch 2. On univariate analysis, early KMC significantly reduced TFF (12.5 vs. 9 days, P < 0.001). Feed intolerance, duration of parenteral nutrition were significantly reduced, and discharge weight Z score improved significantly in epoch 2. On multivariate regression analysis early KMC, exclusive mother's own milk feeding and blood culture-positive late-onset sepsis were important predictors of TFF. Early KMC was safe and well-tolerated. Early KMC was safe and associated with reduced TFF and other nutritional benefits in moderately ill preterm neonates.
Sections du résumé
BACKGROUND
Kangaroo mother care (KMC) is known to reduce neonatal mortality and morbidity. In preterm neonates, KMC is usually initiated only after stabilization.
AIMS
We aimed to assess if early initiation of KMC starting within the first week of life is safe, and reduces the time to full feeds (TFF) in preterm neonates.
STUDY DESIGN
Prospective cohort study.
SUBJECTS
Preterm neonates (Gestation ≤ 34 weeks, Birth weight ≤ 1250 g). This was studied in two epochs, (epoch 1) which was before early KMC vs. epoch 2 which was after implementation of early KMC even if they needed respiratory support, with umbilical/central lines in situ.
OUTCOME
The primary outcome of the study was time to establish full feeds (TFF) of 150 ml/kg/day.
RESULTS
The neonatal demographic characteristics were comparable between epoch 1 and epoch 2 except for lower gestational age, higher surfactant, and any respiratory support in epoch 2. On univariate analysis, early KMC significantly reduced TFF (12.5 vs. 9 days, P < 0.001). Feed intolerance, duration of parenteral nutrition were significantly reduced, and discharge weight Z score improved significantly in epoch 2. On multivariate regression analysis early KMC, exclusive mother's own milk feeding and blood culture-positive late-onset sepsis were important predictors of TFF. Early KMC was safe and well-tolerated.
CONCLUSION
Early KMC was safe and associated with reduced TFF and other nutritional benefits in moderately ill preterm neonates.
Identifiants
pubmed: 33517173
pii: S0378-3782(21)00008-6
doi: 10.1016/j.earlhumdev.2021.105312
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105312Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.