Response of broiler chickens fed diets supplemented with a bioactive olive pomace extract from Olea europaea to an experimental coccidial vaccine challenge.
Eimeria
broiler chicken
coccidiosis
olive pomace extract
vaccine
Journal
Poultry science
ISSN: 1525-3171
Titre abrégé: Poult Sci
Pays: England
ID NLM: 0401150
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
01
06
2020
revised:
04
09
2020
accepted:
09
11
2020
entrez:
1
2
2021
pubmed:
2
2
2021
medline:
22
4
2021
Statut:
ppublish
Résumé
This study aimed to investigate an experimental procedure of coccidial challenge in battery cages and the anticoccidial effect of a bioactive olive pomace extract from Olea europaea (OE) in broiler chickens. To this end, four hundred 1-day-old male chicks were randomly assigned to 5 experimental treatments (10 cages/treatment; 8 birds/cage). One group was fed the control diet without any additives and not challenged (NCU). The other 4 groups were challenged and fed the control diet with no additives (NCC) or supplemented with 500 ppm of coccidiostat or with 500 or 1,500 ppm of OE. At 0, 7, and 14 d, all challenged birds, except the NCC group, were orally gavaged with a live Eimeria spp. oocyst vaccine at 1x, 4x, and 16x of the manufacturer's recommended dose, respectively. Feed intake (FI), body weight gain (BWG), and feed conversion ratio (FCR) were determined at 7, 14, 20, and 28 d. At 20 d of age, 1 bird per cage was euthanized to analyze duodenum and jejunum morphology, ileal mucosa gene expression, and plasma cytokine, alpha-1-acid glycoprotein, and carotenoid (CAR) concentrations. Coccidial vaccine challenge lowered BW (P < 0.05) throughout the trial, and reduced FI and BWG, except from 20 to 28d, and increased FCR from 0 to 7, 0 to 14, and 0 to 20 d. Birds in the NCC group had higher (P < 0.05) oocyst counts and lower (P < 0.05) CAR and villus height to crypt depth ratios compared with NCU birds. Overall, coccidia challenge caused the expected reductions in growth performance and gut integrity. While the coccidiostat reduced oocysts excretion, dietary OE or coccidiostat had no effects on performance or gut integrity. The attenuated inflammatory response observed for all the treatments following the third infection can be attributed to the adaptation or immunization to the repetitive exposure to Eimeria spp.
Identifiants
pubmed: 33518110
pii: S0032-5791(20)30879-8
doi: 10.1016/j.psj.2020.11.027
pmc: PMC7858167
pii:
doi:
Substances chimiques
Plant Extracts
0
Protozoan Vaccines
0
Types de publication
Journal Article
Randomized Controlled Trial, Veterinary
Langues
eng
Sous-ensembles de citation
IM
Pagination
575-584Informations de copyright
Copyright © 2020. Published by Elsevier Inc.
Références
J Sci Food Agric. 2018 Jan;98(1):225-230
pubmed: 28580634
Genomics. 2009 Aug;94(2):146-52
pubmed: 19422910
Front Immunol. 2019 Nov 22;10:2732
pubmed: 31824509
Avian Pathol. 2002 Aug;31(4):317-53
pubmed: 12396335
Poult Sci. 2010 Sep;89(9):1788-801
pubmed: 20709963
Vet J. 2011 Feb;187(2):182-8
pubmed: 20382054
Avian Dis. 1993 Jan-Mar;37(1):118-23
pubmed: 8452488
Poult Sci. 2019 Apr 1;98(4):1622-1633
pubmed: 30481335
Front Vet Sci. 2020 Jan 14;6:468
pubmed: 31993443
Avian Pathol. 2000 Aug;29(4):333-42
pubmed: 19184823
Anim Health Res Rev. 2017 Jun;18(1):26-45
pubmed: 28485263
J Agric Food Chem. 2014 Aug 6;62(31):7915-9
pubmed: 25007306
Poult Sci. 2018 Nov 1;97(11):3947-3956
pubmed: 29945201
Parasitol Res. 2010 Aug;107(3):601-4
pubmed: 20499099
Poult Sci. 1987 Aug;66(8):1306-15
pubmed: 3684853
Br J Nutr. 2017 Feb;117(3):351-363
pubmed: 28245885
Dev Comp Immunol. 2000 Mar-Apr;24(2-3):303-24
pubmed: 10717295
Evid Based Complement Alternat Med. 2016;2016:2657981
pubmed: 27429634
J Dairy Sci. 2017 Mar;100(3):1940-1945
pubmed: 28041739
Vet Parasitol. 2004 May 26;121(3-4):189-212
pubmed: 15135859
Poult Sci. 2006 Jan;85(1):48-55
pubmed: 16493945
Biomed Res Int. 2015;2015:430610
pubmed: 25785269
Poult Sci. 2004 Oct;83(10):1667-74
pubmed: 15510551
Dev Comp Immunol. 2003 Feb;27(2):147-57
pubmed: 12543128
Vet Q. 2011 Sep;31(3):143-61
pubmed: 22029884
Front Vet Sci. 2015 May 26;2:14
pubmed: 26664943
Animals (Basel). 2020 Feb 22;10(2):
pubmed: 32098336
Acta Parasitol. 2019 Dec;64(4):887-897
pubmed: 31493179
Poult Sci. 2020 Jan;99(1):2-10
pubmed: 32416802
Avian Dis. 1990 Oct-Dec;34(4):911-5
pubmed: 2282020
BMC Vet Res. 2015 Mar 25;11:75
pubmed: 25884204
Poult Sci. 2019 Nov 1;98(11):5669-5678
pubmed: 31247645
Br Poult Sci. 2019 Dec;60(6):766-776
pubmed: 31483171
PLoS One. 2017 Mar 27;12(3):e0174239
pubmed: 28346507
Vet Immunol Immunopathol. 2008 Apr 15;122(3-4):312-7
pubmed: 18272235
Poult Sci. 2016 Jul 1;95(7):1573-1581
pubmed: 26933234
Vet Immunol Immunopathol. 2006 Dec 15;114(3-4):209-23
pubmed: 16996141