Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada.


Journal

Poultry science
ISSN: 1525-3171
Titre abrégé: Poult Sci
Pays: England
ID NLM: 0401150

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 20 06 2020
revised: 04 10 2020
accepted: 19 10 2020
entrez: 1 2 2021
pubmed: 2 2 2021
medline: 24 4 2021
Statut: ppublish

Résumé

Increasing resistance of Eimeria species to anticoccidial medications is an issue in the broiler chicken industry. Using drug-sensitive strains in live-coccidiosis vaccines has been shown to improve anticoccidial effectiveness in US-based broiler production. In Canada, litter is removed between flocks, which differ from the US industry practice. Thus, we investigated the use of drug-sensitive vaccine strains in a Canadian broiler production facility with suspected anticoccidial resistance. Weekly fecal samples were collected from flocks before, during, and after vaccine seeding to determine oocyst shedding patterns; following the vaccine seeding, OPG counts from similar aged birds were lower than flocks before live-coccidiosis vaccine use. Eimeria species isolates, collected before and after vaccine seeding, were used in 2 anticoccidial sensitivity tests to evaluate their susceptibility to commercially available anticoccidial medications; a low-dose challenge to define parasite replication, and a high-dose challenge to monitor broiler performance. In both experiments, isolates collected after seeding were more susceptible to almost every anticoccidial medication evaluated compared with the isolates collected before seeding. These results demonstrate an improvement in sensitivity to many anticoccidials after the use of live-coccidiosis vaccines at this facility. However, the regulated removal of litter at the end of each flock required under Canadian broiler chicken production management rules could limit the establishment of vaccine-strain Eimeria species in broiler facilities and could shorten the longevity of improved drug sensitivity observed in this study.

Identifiants

pubmed: 33518120
pii: S0032-5791(20)30795-1
doi: 10.1016/j.psj.2020.10.042
pmc: PMC7858156
pii:
doi:

Substances chimiques

Coccidiostats 0
Protozoan Vaccines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

663-674

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

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Auteurs

R P Snyder (RP)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada. Electronic address: snyderr@uoguelph.ca.

M T Guerin (MT)

Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

B M Hargis (BM)

Division of Agriculture, Department of Poultry Science, University of Arkansas, Fayetteville 72703, USA.

P S Kruth (PS)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

G Page (G)

Research and Development, Trouw Nutrition, Amersfoort 3800 AG, The Netherlands.

E Rejman (E)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

J L Rotolo (JL)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

W Sears (W)

Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

E G Zeldenrust (EG)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

J Whale (J)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

J R Barta (JR)

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

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Classifications MeSH