Precision Medicine and Obesity.
Nutrigenomics
Obesity
Personalized nutrition
Phenotype
Precision medicine
Journal
Gastroenterology clinics of North America
ISSN: 1558-1942
Titre abrégé: Gastroenterol Clin North Am
Pays: United States
ID NLM: 8706257
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
entrez:
1
2
2021
pubmed:
2
2
2021
medline:
26
10
2021
Statut:
ppublish
Résumé
The highly variable response to obesity therapies justifies the search for treatment strategies that are best suited to individual patients to enhance their effectiveness and tolerability via precision medicine. Precision medicine development in recent years has been driven by the emergence of powerful methods to characterize patients ("omic" assays). Current available information has revealed that there are numerous intermediary processes that contribute to obesity and have provided a framework for partially comprehending the mechanisms behind the heterogeneity of obesity and its clinical consequences. Some of these processes have or are currently being targeted to individualize obesity therapy with some success.
Identifiants
pubmed: 33518159
pii: S0889-8553(20)30098-4
doi: 10.1016/j.gtc.2020.10.005
pmc: PMC7863578
mid: NIHMS1640016
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
127-139Subventions
Organisme : NIDDK NIH HHS
ID : K23 DK114460
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure M.D. Hurtado A has nothing to disclose. A. Acosta is a stockholder in Gila Therapeutics and Phenomix Sciences; and serves as a consultant for Rhythm Pharmaceuticals and General Mills.
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