coronavirus disease 2019
dissolution
hydroxychloroquine sulfate
pH
validation
Journal
Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173
Informations de publication
Date de publication:
2020
2020
Historique:
received:
02
10
2020
accepted:
30
11
2020
entrez:
1
2
2021
pubmed:
2
2
2021
medline:
2
2
2021
Statut:
epublish
Résumé
Hydroxychloroquine sulfate is one of an extensive series of 4-aminoquinolines with antimalarial activity. Moreover, it is used for the treatment of rheumatoid arthritis. Sometimes, hydroxychloroquine sulfate is beneficial for the treatment of autoimmune diseases. Based on recent clinical experiments, it is exploited for the treatment of COVID-19, coronavirus across the globe. The chromatogram separation was achieved by using Agilent, Zorbax C8, 250 mm × 4.6 mm i.d., column. The buffer consists of 0.01 M of 1-pentane sulfonic acid and 0.02% of orthophosphoric acid in purified water. Mixed buffer, acetonitrile, and methanol (800:100:100 v/v). The flow rate was 1.0 ml min
Identifiants
pubmed: 33521056
doi: 10.3389/fmolb.2020.613393
pmc: PMC7841110
doi:
Types de publication
Journal Article
Langues
eng
Pagination
613393Informations de copyright
Copyright © 2021 Dongala, Katari, Ettaboina, Krishnan, Tambuwala and Dua.
Déclaration de conflit d'intérêts
TD and SE were employed by the company Aurex Laboratories LLC, 10 lake drive, East Windsor, NJ, USA 08512. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Pharm Biomed Anal. 2009 May 1;49(4):873-9
pubmed: 19201565
Cell Res. 2020 Mar;30(3):269-271
pubmed: 32020029
J Chromatogr. 1985 Mar 22;338(2):422-7
pubmed: 3873466
J Chromatogr B Biomed Appl. 1995 Apr 21;666(2):347-53
pubmed: 7633613
J Chromatogr. 1993 Apr 2;613(2):303-10
pubmed: 8491817
J Chromatogr. 1992 Oct 2;581(1):83-92
pubmed: 1430010
Int J Antimicrob Agents. 2020 Apr;55(4):105932
pubmed: 32145363
Clin Chim Acta. 2013 Jun 5;421:79-84
pubmed: 23485647
J Chromatogr. 1986 Apr 25;377:454-9
pubmed: 3711242
Clin Infect Dis. 2020 Jul 28;71(15):732-739
pubmed: 32150618
J Pharm Biomed Anal. 2012 Mar 5;61:86-92
pubmed: 22197155
Biosci Trends. 2020 Mar 16;14(1):72-73
pubmed: 32074550
J Pharm Biomed Anal. 2014 Jul;95:200-6
pubmed: 24682018
J Anal Toxicol. 1994 Sep;18(5):255-60
pubmed: 7990442
J Pharm Biomed Anal. 2003 Jun 1;32(2):269-75
pubmed: 12763536