Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population.
Adult
Age-Specific Death Rate
COVID-19
France
SARS-CoV-2
Journal
Infectious diseases now
ISSN: 2666-9919
Titre abrégé: Infect Dis Now
Pays: France
ID NLM: 101775152
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
08
12
2020
revised:
25
12
2020
accepted:
28
12
2020
pubmed:
2
2
2021
medline:
24
6
2021
entrez:
1
2
2021
Statut:
ppublish
Résumé
This study aimed at estimating the SARS-CoV-2 infection hospitalization (IHR) and infection fatality ratios (IFR) in France. A serosurvey was conducted in 9782 subjects from the two French regions with the highest incidence of COVID-19 during the first wave of the pandemic and coupled with surveillance data. IHR and IFR were 2.7% and 0.49% overall. Both were higher in men and increased exponentially with age. The relative risks of hospitalization and death were 2.1 (95% CI: 1.9-2.3) and 3.8 (2.4-4.2) per 10-year increase, meaning that IHR and IFR approximately doubled every 10 and 5 years, respectively. They were dramatically high in the very elderly (80-90 years: IHR: 26%, IFR: 9.2%), and also substantial in younger adults (40-50 years: IHR: 0.98%, IFR: 0.042%). These findings support the need for comprehensive preventive measures to help reduce the spread of the virus, even in young or middle-aged adults.
Identifiants
pubmed: 33521775
doi: 10.1016/j.idnow.2020.12.007
pii: S2666-9919(20)00032-9
pmc: PMC7836556
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
380-382Informations de copyright
© 2020 Elsevier Masson SAS. All rights reserved.
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