N-Heterocyclic carbene (NHC)-catalyzed intramolecular benzoin condensation-oxidation.
Journal
Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995
Informations de publication
Date de publication:
25 Feb 2021
25 Feb 2021
Historique:
pubmed:
2
2
2021
medline:
2
2
2021
entrez:
1
2
2021
Statut:
ppublish
Résumé
NHC-Catalyzed intramolecular benzoin condensation-oxidation is developed for the expedient synthesis of diverse cyclic 1,2-diketones incorporated in dibenzo-fused seven-membered heterocycles in good to excellent yields, under ambient conditions. The presented carbene-catalyzed transformation appears to proceed through the benzoin intermediate followed by aerobic oxidation.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM