Antigen receptor repertoires of one of the smallest known vertebrates.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
01 2021
Historique:
received: 14 07 2020
accepted: 04 11 2020
entrez: 1 2 2021
pubmed: 2 2 2021
medline: 16 4 2022
Statut: epublish

Résumé

The rules underlying the structure of antigen receptor repertoires are not yet fully defined, despite their enormous importance for the understanding of adaptive immunity. With current technology, the large antigen receptor repertoires of mice and humans cannot be comprehensively studied. To circumvent the problems associated with incomplete sampling, we have studied the immunogenetic features of one of the smallest known vertebrates, the cyprinid fish

Identifiants

pubmed: 33523858
pii: 7/1/eabd8180
doi: 10.1126/sciadv.abd8180
pmc: PMC7775753
pii:
doi:

Substances chimiques

Receptors, Antigen, T-Cell 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Auteurs

Orlando B Giorgetti (OB)

Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, 79108 Freiburg, Germany.

Prashant Shingate (P)

Institute of Molecular and Cell Biology, A*STAR, Biopolis, Singapore 138673, Singapore.

Connor P O'Meara (CP)

Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, 79108 Freiburg, Germany.

Vydianathan Ravi (V)

Institute of Molecular and Cell Biology, A*STAR, Biopolis, Singapore 138673, Singapore.

Nisha E Pillai (NE)

Institute of Molecular and Cell Biology, A*STAR, Biopolis, Singapore 138673, Singapore.

Boon-Hui Tay (BH)

Institute of Molecular and Cell Biology, A*STAR, Biopolis, Singapore 138673, Singapore.

Aravind Prasad (A)

Institute of Molecular and Cell Biology, A*STAR, Biopolis, Singapore 138673, Singapore.

Norimasa Iwanami (N)

Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, 79108 Freiburg, Germany.

Heok Hui Tan (HH)

Lee Kong Chian Natural History Museum, National University of Singapore, Singapore 117377, Singapore.

Michael Schorpp (M)

Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, 79108 Freiburg, Germany.

Byrappa Venkatesh (B)

Institute of Molecular and Cell Biology, A*STAR, Biopolis, Singapore 138673, Singapore. boehm@ie-freiburg.mpg.de mcbbv@imcb.a-star.edu.sg.

Thomas Boehm (T)

Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, 79108 Freiburg, Germany. boehm@ie-freiburg.mpg.de mcbbv@imcb.a-star.edu.sg.

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Classifications MeSH