Mga safeguards embryonic stem cells from acquiring extraembryonic endoderm fates.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
01
09
2020
accepted:
24
11
2020
entrez:
1
2
2021
pubmed:
2
2
2021
medline:
19
4
2022
Statut:
epublish
Résumé
Polycomb group (PcG) proteins form multiprotein complexes that affect stem cell identity and fate decisions by still largely unexplored mechanisms. Here, by performing a CRISPR-based loss-of-function screen in embryonic stem cells (ESCs), we identify PcG gene
Identifiants
pubmed: 33523934
pii: 7/4/eabe5689
doi: 10.1126/sciadv.abe5689
pmc: PMC7821913
pii:
doi:
Substances chimiques
Basic Helix-Loop-Helix Transcription Factors
0
GATA6 Transcription Factor
0
Mga protein, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).
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