Genetic Background and Inbreeding Depression in Romosinuano Cattle Breed in Mexico.
Romosinuano
autozygosity
effective population size
inbreeding
inbreeding depression
runs of homozygosity
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
28 Jan 2021
28 Jan 2021
Historique:
received:
09
11
2020
revised:
22
01
2021
accepted:
26
01
2021
entrez:
2
2
2021
pubmed:
3
2
2021
medline:
3
2
2021
Statut:
epublish
Résumé
The ultimate goal of genetic selection is to improve genetic progress by increasing favorable alleles in the population. However, with selection, homozygosity, and potentially harmful recessive alleles can accumulate, deteriorating genetic variability and hampering continued genetic progress. Such potential adverse side effects of selection are of particular interest in populations with a small effective population size like the Romosinuano beef cattle in Mexico. The objective of this study was to evaluate the genetic background and inbreeding depression in Mexican Romosinuano cattle using pedigree and genomic information. Inbreeding was estimated using pedigree (FPED) and genomic information based on the genomic relationship matrix (FGRM) and runs of homozygosity (FROH) of different length classes. Linkage disequilibrium (LD) was evaluated using the correlation between pairs of loci, and the effective population size (Ne
Identifiants
pubmed: 33525405
pii: ani11020321
doi: 10.3390/ani11020321
pmc: PMC7911603
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Anim Sci. 1997 Apr;75(4):934-40
pubmed: 9110204
Genome Res. 2003 Apr;13(4):635-43
pubmed: 12654718
BMC Genet. 2012 Aug 14;13:70
pubmed: 22888858
Genet Sel Evol. 2003 Jan-Feb;35(1):43-63
pubmed: 12605850
J Anim Breed Genet. 2005 Jun;122(3):172-6
pubmed: 16130468
J Dairy Sci. 2008 May;91(5):2106-17
pubmed: 18420642
Am J Hum Genet. 2007 Sep;81(3):559-75
pubmed: 17701901
J Anim Breed Genet. 2012 Aug;129(4):257-70
pubmed: 22775258
J Dairy Sci. 2008 Nov;91(11):4414-23
pubmed: 18946147
Front Genet. 2015 Mar 20;6:109
pubmed: 25852748
Theor Popul Biol. 1973 Mar;4(1):129-32
pubmed: 4726005
Sci Rep. 2020 Sep 7;10(1):14701
pubmed: 32895448
J Anim Sci. 2019 Jan 1;97(1):1-18
pubmed: 30304409
J Anim Breed Genet. 2013 Aug;130(4):286-93
pubmed: 23855630
Animals (Basel). 2019 Mar 06;9(3):
pubmed: 30845681
J Dairy Sci. 2018 Dec;101(12):11097-11107
pubmed: 30316595
Anim Genet. 2014 Oct;45(5):618-28
pubmed: 24975026
BMC Genomics. 2020 Jan 29;21(1):94
pubmed: 31996125
Hum Mol Genet. 2006 Mar 1;15(5):789-95
pubmed: 16436455
Anim Genet. 2018 Oct;49(5):371-383
pubmed: 30070013
BMC Genomics. 2020 Sep 1;21(1):605
pubmed: 32873253
J Anim Breed Genet. 2009 Aug;126(4):327-32
pubmed: 19630884
J Anim Breed Genet. 2021 Jan;138(1):69-79
pubmed: 33263211
J Dairy Sci. 2020 Jun;103(6):5302-5313
pubmed: 32331889
BMC Genet. 2015 Jul 22;16:88
pubmed: 26195126
PLoS One. 2020 Aug 27;15(8):e0237818
pubmed: 32853245
J Anim Breed Genet. 2010 Oct;127(5):339-47
pubmed: 20831557
Genet Sel Evol. 2008 Jul-Aug;40(4):359-78
pubmed: 18558071
Genet Mol Biol. 2018 Apr./Jun;41(2):426-433
pubmed: 30088613
J Anim Sci. 2020 Dec 1;98(12):
pubmed: 33180906
Int J Biol Sci. 2012;8(6):838-58
pubmed: 22745575
Am J Hum Genet. 1999 Dec;65(6):1493-500
pubmed: 10577902
Anim Genet. 2015 Apr;46(2):110-21
pubmed: 25530322
BMC Genomics. 2010 Jul 08;11:421
pubmed: 20609259
PLoS One. 2010 Nov 15;5(11):e13996
pubmed: 21085596
Genet Sel Evol. 2019 Sep 27;51(1):54
pubmed: 31558150
Animals (Basel). 2020 Dec 03;10(12):
pubmed: 33287320
PLoS Genet. 2012;8(11):e1003100
pubmed: 23209444
Evol Appl. 2018 May 18;12(1):105-122
pubmed: 30622639
Genome Res. 2007 Apr;17(4):520-6
pubmed: 17351134
BMC Genomics. 2015 Oct 28;16:872
pubmed: 26510479
Genet Sel Evol. 2014 Nov 18;46:71
pubmed: 25407532