Theranostic Design of Angiopep-2 Conjugated Hyaluronic Acid Nanoparticles (Thera-ANG-cHANPs) for Dual Targeting and Boosted Imaging of Glioma Cells.
BBB
MRI
active targeting
angiopep-2
glioblastoma
hyaluronic acid
hydrodenticity
irinotecan
nanomedicine
precision medicine
theranostics
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
28 Jan 2021
28 Jan 2021
Historique:
received:
03
12
2020
revised:
08
01
2021
accepted:
22
01
2021
entrez:
2
2
2021
pubmed:
3
2
2021
medline:
3
2
2021
Statut:
epublish
Résumé
Glioblastoma multiforme (GBM) has a mean survival of only 15 months. Tumour heterogeneity and blood-brain barrier (BBB) mainly hinder the transport of active agents, leading to late diagnosis, ineffective therapy and inaccurate follow-up. The use of hydrogel nanoparticles, particularly hyaluronic acid as naturally occurring polymer of the extracellular matrix (ECM), has great potential in improving the transport of drug molecules and, furthermore, in facilitatating the early diagnosis by the effect of hydrodenticity enabling the T
Identifiants
pubmed: 33525655
pii: cancers13030503
doi: 10.3390/cancers13030503
pmc: PMC7865309
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ministero dell'Università e della Ricerca
ID : 2017MHJJ55
Références
Contrast Media Mol Imaging. 2018 Dec 2;2018:6828396
pubmed: 30627060
Biophys Rev. 2016 Dec;8(4):409-427
pubmed: 28510011
Toxics. 2017 Jul 19;5(3):
pubmed: 29051447
Sci Rep. 2016 Nov 30;6:37906
pubmed: 27901092
Nanomedicine (Lond). 2018 Jul;13(13):1595-1606
pubmed: 30028222
Genes Dis. 2016 May 11;3(3):198-210
pubmed: 30258889
Mol Imaging Biol. 2018 Oct;20(5):683-695
pubmed: 30084044
Cell Adh Migr. 2008 Jul-Sep;2(3):202-7
pubmed: 19262113
J Cell Mol Med. 2010 Dec;14(12):2827-39
pubmed: 19818094
Nanomedicine (Lond). 2017 Sep;12(18):2199-2210
pubmed: 28816102
Curr Opin Oncol. 2018 Jan;30(1):54-60
pubmed: 29135607
Nat Biotechnol. 2015 Sep;33(9):941-51
pubmed: 26348965
Neurooncol Pract. 2016 Mar;3(1):59-67
pubmed: 31579522
Sci Rep. 2020 Apr 7;10(1):6028
pubmed: 32265496
Nat Rev Mater. 2016 Dec;1(12):
pubmed: 29657852
Int J Nanomedicine. 2017 Apr 18;12:3137-3151
pubmed: 28458536
Cytometry A. 2013 Feb;83(2):197-204
pubmed: 23081720
Cancer Res. 2009 May 15;69(10):4167-74
pubmed: 19435897
Front Bioeng Biotechnol. 2020 Mar 20;8:210
pubmed: 32266237
Biomaterials. 2012 Feb;33(5):1673-81
pubmed: 22133551
Magn Reson Imaging. 2018 Oct;52:16-23
pubmed: 29777820
Mol Cancer Res. 2014 Oct;12(10):1416-29
pubmed: 24962319
Vascul Pharmacol. 2002 Jun;38(6):339-48
pubmed: 12529928
Nanomedicine. 2015 Nov;11(8):1893-907
pubmed: 26282377
Hum Pathol. 2013 Oct;44(10):2081-8
pubmed: 23791210
Br J Radiol. 2019 Jan;92(1093):20180365
pubmed: 30226413
Cancer Cell. 2017 Mar 13;31(3):326-341
pubmed: 28292436
Biomaterials. 2012 Nov;33(32):8167-76
pubmed: 22889488
Nanomedicine (Lond). 2012 Aug;7(8):1225-33
pubmed: 22931448
Nanotheranostics. 2018 Jan 1;2(1):70-86
pubmed: 29291164
Neuro Oncol. 2013 Dec;15(12):1684-95
pubmed: 24046260
Nat Biomed Eng. 2019 Mar;3(3):230-245
pubmed: 30948807
J Pharmacol Exp Ther. 2008 Mar;324(3):1064-72
pubmed: 18156463
Lancet Oncol. 2017 Jun;18(6):e315-e329
pubmed: 28483413
Neurosurg Focus. 2014 Dec;37(6):E9
pubmed: 25581938
J Hazard Mater. 2011 Jun 15;190(1-3):366-74
pubmed: 21493003
Carbohydr Polym. 2019 Oct 15;222:114991
pubmed: 31320060
Nanomedicine. 2011 Dec;7(6):818-26
pubmed: 21453790
Nat Nanotechnol. 2012 Oct;7(10):623-9
pubmed: 23042546
Biotechnol Annu Rev. 2005;11:227-56
pubmed: 16216779
Sci Rep. 2017 Mar 22;7:45121
pubmed: 28327584
Theranostics. 2019 Feb 28;9(6):1809-1824
pubmed: 31037140
AJNR Am J Neuroradiol. 2011 Dec;32(11):1978-85
pubmed: 21393407
J Biol Chem. 1994 Nov 25;269(47):29874-82
pubmed: 7961982
PLoS One. 2015 May 18;10(5):e0127058
pubmed: 25993039
Nanomedicine (Lond). 2017 Sep;12(18):2211-2222
pubmed: 28814137
Gene Ther. 2015 Dec;22(12):947-59
pubmed: 26196249
Nat Rev Neurosci. 2007 Aug;8(8):610-22
pubmed: 17643088
J Control Release. 2016 Dec 28;244(Pt A):108-121
pubmed: 27871992
Cancers (Basel). 2018 Dec 20;11(1):
pubmed: 30577488
Br J Cancer. 1997;75(6):829-36
pubmed: 9062403
AJNR Am J Neuroradiol. 2015 May;36(5):877-85
pubmed: 25593202
Nat Rev Clin Oncol. 2010 Nov;7(11):653-64
pubmed: 20838415
Rev Neurosci. 2016 Aug 1;27(6):623-34
pubmed: 27206317
Pharmaceutics. 2020 Apr 17;12(4):
pubmed: 32316537
Cancer Res. 2000 Apr 15;60(8):2300-3
pubmed: 10786698
Neuro Oncol. 2018 Jan 22;20(2):184-191
pubmed: 29016900